Department of Neurology, Iizuka Hospital, Japan.
Department of Neurology, National Hospital Organization Beppu Medical Center, Japan.
Intern Med. 2021 Dec 15;60(24):3987-3990. doi: 10.2169/internalmedicine.7024-21. Epub 2021 Jun 26.
Platypnea-orthodeoxia syndrome is a rare clinical entity characterized by dyspnea and arterial blood deoxygenation in a sitting position. An 89-year-old woman was diagnosed with subacute cerebellar infarction. Her blood oxygen saturation decreased to 88% in a sitting position, resulting in dyspnea. Cardiological thoracic computed tomography revealed an unruptured aortic aneurysm, an enlarged ascending aorta, right atrial compression, and counterclockwise rotation of the heart. An anatomical distortion of the atrial septum induced by these abnormalities directed the atrial venous inflow such that the right-left shunt flow was exacerbated in a sitting position.
直立位呼吸窘迫-低氧血症综合征是一种罕见的临床病症，其特征为患者在坐姿时出现呼吸困难和动脉血氧饱和度降低。一位 89 岁女性被诊断为亚急性小脑梗死。她在坐姿时血氧饱和度下降至 88%，导致呼吸困难。心脏 CT 显示未破裂的主动脉夹层瘤、升主动脉增宽、右心房受压和心脏逆时针旋转。这些异常导致房间隔解剖结构扭曲，使得静脉回流方向改变，右向左分流在坐姿时加重。
