1Department of Odontology, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; 2Dental Center Cassandraplein, Eindhoven, The Netherlands; 3Department of Medical Informatics and Biostatistics, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; 4Department of Pathophysiology, Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, Romania.
Acta Clin Croat. 2020 Sep;59(3):513-522. doi: 10.20471/acc.2020.59.03.16.
Oral lichen planus (OLP) is a disease with unclear etiology or pathogenesis, categorized by the World Health Organization as oral lichenoid lesions (OLL; interface mucositis or lichenoid mucositis) into a group of potentially malignant disorders. The diagnosis of OLP is challenging because the clinical and histopathologic features are frequently seen in OLP, OLL and/or other mucosal diseases with lichenoid characteristics. Furthermore, OLP has a dynamic nature. Finally, an early and precise diagnosis can play a decisive role, allowing timely treatment and thus improving the patient quality of life. This article summarizes the state-of-the-art regarding OLP and OLL and discusses the challenges faced on making an accurate diagnosis, aiming to provide a practical guideline for the postgraduates and oral physicians in reaching the diagnosis of these lesions.
口腔扁平苔藓(OLP)是一种病因或发病机制尚不清楚的疾病,世界卫生组织(WHO)将其归类为口腔类疾病(OLL;界面黏膜炎或苔藓样黏膜炎)中的一组潜在恶性疾病。OLP 的诊断具有挑战性,因为 OLP、OLL 和/或其他具有苔藓样特征的黏膜疾病常出现 OLP 的临床和组织病理学特征。此外,OLP 具有动态性质。最后,早期和准确的诊断可以起到决定性的作用,及时治疗从而提高患者的生活质量。本文总结了 OLP 和 OLL 的最新研究进展,并讨论了准确诊断所面临的挑战,旨在为研究生和口腔医生提供这些病变诊断的实用指南。