Humblot Patrice
Division of Reproduction, Department of Clinical Sciences, SLU, Uppsala, Sweden.
Anim Reprod. 2018 Aug 17;15(3):278-291. doi: 10.21451/1984-3143-AR2018-0076.
This manuscript describes the different topics I have been involved in the fields of reproductive physiology and embryo biotechnologies with attempts to address practical issues raised mainly by the breeding industry. The journey started with phenotyping work in the field of reproductive physio-pathology. Other issues were related to the optimization of reproductive biotechnologies to favorize genetic selection. The implementation of genomic selection raised opportunities to develop the use embryo biotechnologies and showed the interest of combining them in the case of embryo genotyping. There is still a need to refine phenotyping for reproductive traits especially for the identification of markers of uterine dysfunction. It is believed that new knowledge generated by combining different molecular approaches will be the source of applications that may benefit AI practice and embryo technologies.
本手稿描述了我在生殖生理学和胚胎生物技术领域所涉及的不同主题,旨在解决主要由育种行业提出的实际问题。这段历程始于生殖生理病理学领域的表型分析工作。其他问题则与生殖生物技术的优化有关,以促进基因选择。基因组选择的实施为发展胚胎生物技术的应用带来了机遇,并显示了在胚胎基因分型中将它们结合起来的意义。仍有必要完善生殖性状的表型分析,特别是子宫功能障碍标志物的识别。人们相信,通过结合不同分子方法产生的新知识将成为可能有益于人工授精实践和胚胎技术的应用来源。