Cortassa Sonia, Aon Miguel A
Laboratory of Cardiovascular Science, National Institute on Aging, NIH, Baltimore, MD USA.
Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD USA.
Biophys Rev. 2021 May 24;13(3):311-314. doi: 10.1007/s12551-021-00808-7. eCollection 2021 Jun.
A distinguished group of researchers congregated at one of the symposia during the 2021 Virtual Meeting organized by the Biophysical Society, to speak about the critically important role played by mitochondrial functionality in healthy aging. The latest research trends expressed by the speakers during the meeting resulted in an updated display of novel emerging molecular targets involved in keeping mitochondrial health during metabolic disorder and until late in life. Besides offering insightful views on the impact of mitochondrial healthy function on the biology of aging in different organs such as the liver and cardiac and skeletal muscle, their distinct experimental approaches showed a significant convergence in results, a reassuring hallmark of scientific excellence. The interdisciplinary crossroad of biology, biophysics, and biochemistry, evidenced during the symposium organized by the Bioenergetics, Mitochondria, and Metabolism subgroup, is another example of fruitful collaboration at one of the scientific frontiers represented by human aging.
在生物物理学会组织的2021年虚拟会议期间，一群杰出的研究人员聚集在其中一场研讨会上，探讨线粒体功能在健康衰老过程中所起的至关重要的作用。会议期间发言者所展示的最新研究趋势，带来了有关在代谢紊乱直至生命后期维持线粒体健康所涉及的新兴分子靶点的最新展示。除了对线粒体健康功能对肝脏、心脏和骨骼肌等不同器官衰老生物学的影响提供深刻见解外，他们独特的实验方法在结果上显示出显著的趋同性，这是科学卓越性的一个令人安心的标志。由生物能量学、线粒体与代谢小组组织的研讨会上所体现的生物学、生物物理学和生物化学的跨学科交叉点，是人类衰老所代表的科学前沿之一富有成效的合作的另一个例子。
