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新型冠状病毒肺炎与妊娠:一项病例研究。

COVID-19 and Pregnancy: A Case Study.

作者信息

Long Rui, Wu Di, Lin Xingguang, Lv Dan, Wang Renjie, Jin Lei, Liao Shujie, Liu Weiliang, Deng Dongrui

机构信息

Department of Obstetrics Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China.

Department of Obstetrics Caidian District People's Hospital Wuhan 430100 China.

出版信息

Glob Chall. 2021 May 13;5(8):2000074. doi: 10.1002/gch2.202000074. eCollection 2021 Aug.

Abstract

The 2019 novel coronavirus disease is spreading all over the world. Pregnant women and infants require particular concern, owing to the special immune conditions. A case of a pregnant woman who was exposed to SARS-CoV-2 at 34+1 weeks gestation and chose to continue pregnancy is reported. Without obvious symptoms or signs, the woman did not receive any treatment before delivery, and gave birth at 37+5 weeks to a neonate with positive immunoglobulin G for SARS-CoV-2 and negative nucleic acid tests. The mother was given anti-infection, oxytocin, and fluid rehydration treatment after delivery. Both mother and infant recovered well after a three-month follow-up. Continued expectation to deliver at term instead of preterm can decrease the potential risk of severe perinatal and infant complications and is beneficial to the development of the neonate. More studies are required to confirm the presence of vertical transmission.

摘要

2019年新型冠状病毒病正在全球蔓延。由于特殊的免疫状况,孕妇和婴儿需要特别关注。本文报告了1例在妊娠34 + 1周时接触严重急性呼吸综合征冠状病毒2(SARS-CoV-2)并选择继续妊娠的孕妇病例。该孕妇无明显症状或体征,分娩前未接受任何治疗,于妊娠37 + 5周分娩出1例新生儿,其免疫球蛋白G针对SARS-CoV-2呈阳性,但核酸检测呈阴性。产后给予母亲抗感染、缩宫素及补液治疗。经过3个月的随访,母婴恢复良好。继续期待足月分娩而非早产可降低围产期和婴儿严重并发症的潜在风险,并有利于新生儿的发育。需要更多研究来证实垂直传播的存在。

相似文献

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COVID-19 and Pregnancy: A Case Study.新型冠状病毒肺炎与妊娠:一项病例研究。
Glob Chall. 2021 May 13;5(8):2000074. doi: 10.1002/gch2.202000074. eCollection 2021 Aug.

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Neonatal jaundice: aetiology, diagnosis and treatment.新生儿黄疸:病因、诊断与治疗
Br J Hosp Med (Lond). 2017 Dec 2;78(12):699-704. doi: 10.12968/hmed.2017.78.12.699.
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Zika Virus and Birth Defects--Reviewing the Evidence for Causality.寨卡病毒与出生缺陷——因果关系证据综述
N Engl J Med. 2016 May 19;374(20):1981-7. doi: 10.1056/NEJMsr1604338. Epub 2016 Apr 13.
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Born too soon: preterm birth matters.早产:出生过早不容忽视。
Reprod Health. 2013;10 Suppl 1(Suppl 1):S1. doi: 10.1186/1742-4755-10-S1-S1. Epub 2013 Nov 15.

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