Li Fulun, Liu Ke, Zhao Qianlong, Chen Junyi, Liu Lingfei, Xie Qingmu, Yang Jing
Department of Child Development and Behavior Children's Hospital of Gansu Province Lanzhou University Second Hospital Lanzhou Gansu China.
School of Applied Chemical Engineering Lanzhou Petrochemical Polytechnic Lanzhou Gansu China.
Pediatr Investig. 2021 Jan 25;5(2):140-147. doi: 10.1002/ped4.12233. eCollection 2021 Jun.
The prevalence and characteristics of short stature (SS) among children in China should be assessed to provide guidance for planning and implementation of nationwide public health policies. Thus far, there have been no accurate estimates of the prevalence of SS in China.
To analyze the prevalence of SS among children in China and to explore the influences of sex, area, age, study year, and study site on prevalence rates.
Relevant literature was identified by searching the following databases: PubMed, Embase, The Cochrane Library, Chinese Biomedical Literature, China Knowledge Resource Integrated, WeiPu, and WanFang databases. Meta-analysis was carried out using STATA 11.2.
This meta-analysis included 39 studies with 348 326 Chinese participants; the studies covered 20 provinces, municipalities, and autonomous regions. The pooled prevalence of SS was 3.2% (95% confidence interval [], 2.6%-3.7%; = 99.8%). The prevalence of SS in boys and girls were 3.1% (95% , 2.5%-3.7%) and 3.2% (95% , 2.6%-3.9%), respectively. The sex difference was not statistically significant ( 0.05). The prevalence of SS was higher in rural areas than in urban areas (4.7% [95% , 3.6%-5.8%] vs. 2.8% [95% , 2.2%-3.4%]; 0.001). The prevalence of SS was higher in West China (5.2%; 95% , 4.4%-6.0%) than in Northeast China (0.6%; 95% , 0.3%-0.8%), East China (2.3%; 95% , 1.9%-2.8%), or Central China (2.9%; 95% , 1.9%-3.9%).
The prevalence of SS among children was higher in western and rural areas of China. Close attention to children's growth and development is needed to prevent the occurrence of SS.
应评估中国儿童矮小症（SS）的患病率及特征，为全国公共卫生政策的规划与实施提供指导。迄今为止，尚无中国SS患病率的准确估计值。
分析中国儿童SS的患病率，并探讨性别、地区、年龄、研究年份和研究地点对患病率的影响。
通过检索以下数据库确定相关文献：PubMed、Embase、Cochrane图书馆、中国生物医学文献数据库、中国知网、维普和万方数据库。使用STATA 11.2进行荟萃分析。
该荟萃分析纳入了39项研究，共348326名中国参与者；这些研究覆盖了20个省、直辖市和自治区。SS的合并患病率为3.2%（95%置信区间[，2.6%-3.7%]； = 99.8%）。男孩和女孩的SS患病率分别为3.1%（95% ，2.5%-3.7%）和3.2%（95% , 2.6%-3.9%）。性别差异无统计学意义（ 0.05）。农村地区SS的患病率高于城市地区（4.7% [95% ，3.6%-5.8%] 对2.8% [95% ，2.2%-3.4%]； 0.001）。中国西部地区SS的患病率（5.2%；95% ，4.4%-6.0%）高于东北地区（0.6%；95% ，0.3%-0.8%）、东部地区（2.3%；95% ，1.9%-2.8%）或中部地区（2.9%；95% ，1.9%-3.9%）。
中国儿童SS的患病率在西部和农村地区较高。需要密切关注儿童的生长发育，以预防SS的发生。
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