de Onis Mercedes, Branca Francesco
Department of Nutrition for Health and Development, World Health Organization, Geneva, Switzerland.
Matern Child Nutr. 2016 May;12 Suppl 1(Suppl 1):12-26. doi: 10.1111/mcn.12231.
Childhood stunting is the best overall indicator of children's well-being and an accurate reflection of social inequalities. Stunting is the most prevalent form of child malnutrition with an estimated 161 million children worldwide in 2013 falling below -2 SD from the length-for-age/height-for-age World Health Organization Child Growth Standards median. Many more millions suffer from some degree of growth faltering as the entire length-for-age/height-for-age z-score distribution is shifted to the left indicating that all children, and not only those falling below a specific cutoff, are affected. Despite global consensus on how to define and measure it, stunting often goes unrecognized in communities where short stature is the norm as linear growth is not routinely assessed in primary health care settings and it is difficult to visually recognize it. Growth faltering often begins in utero and continues for at least the first 2 years of post-natal life. Linear growth failure serves as a marker of multiple pathological disorders associated with increased morbidity and mortality, loss of physical growth potential, reduced neurodevelopmental and cognitive function and an elevated risk of chronic disease in adulthood. The severe irreversible physical and neurocognitive damage that accompanies stunted growth poses a major threat to human development. Increased awareness of stunting's magnitude and devastating consequences has resulted in its being identified as a major global health priority and the focus of international attention at the highest levels with global targets set for 2025 and beyond. The challenge is to prevent linear growth failure while keeping child overweight and obesity at bay.
儿童发育迟缓是衡量儿童福祉的最佳综合指标,也是社会不平等的准确反映。发育迟缓是儿童营养不良最普遍的形式,据估计,2013年全球有1.61亿儿童的身高低于世界卫生组织儿童生长标准中年龄别身长/年龄别身高中位数的-2标准差。还有数百万儿童存在一定程度的生长发育迟缓,因为整个年龄别身长/年龄别身高z评分分布向左偏移,这表明所有儿童,而不仅仅是那些低于特定临界值的儿童,都受到了影响。尽管全球对于如何定义和衡量发育迟缓已达成共识,但在一些社区中,发育迟缓往往未被认识到,因为在这些社区中身材矮小是常态,而且在初级卫生保健机构中通常不会常规评估线性生长情况,也很难通过视觉识别出发育迟缓。生长发育迟缓往往始于子宫内,并至少持续到出生后的头两年。线性生长失败是多种病理疾病的标志,这些疾病与发病率和死亡率增加、身体生长潜力丧失、神经发育和认知功能降低以及成年后患慢性病的风险升高有关。发育迟缓所伴随的严重且不可逆转的身体和神经认知损害对人类发展构成了重大威胁。人们对发育迟缓的严重程度及其破坏性后果的认识不断提高,这使得发育迟缓被确定为一项重大的全球卫生重点,成为国际最高层面关注的焦点,并设定了2025年及以后的全球目标。挑战在于预防线性生长失败,同时控制儿童超重和肥胖问题。