Nowakowska-Płaza Anna, Wroński Jakub, Płaza Mateusz, Sudoł-Szopińska Iwona, Głuszko Piotr
Department of Rheumatology, National Institute of Geriatrics, Rheumatology, and Rehabilitation, Warsaw, Poland
Department of Rheumatology, National Institute of Geriatrics, Rheumatology, and Rehabilitation, Warsaw, Poland.
Pol Arch Intern Med. 2021 Sep 30;131(9):840-847. doi: 10.20452/pamw.16046. Epub 2021 Jun 25.
Osteoporosis is still underdiagnosed in Poland, partly due to limited accessibility to the gold-standard diagnostic technique, that is, dual-energy X-ray absorptiometry (DXA) of the proximal femur and lumbar spine. The use of radiofrequency echographic multispectrometry (REMS) as an alternative diagnostic tool might be of particular interest because this technique is nonionizing, the devices are portable, and their utilization relatively cheap.
The aim of this study was to assess the agreement between a novel quantitative technique (REMS) and DXA in the evaluation of bone mineral density and diagnosis of osteoporosis.
All recruited patients (n = 116) underwent DXA and REMS of the proximal femur and lumbar spine. The diagnostic agreement of REMS was assessed through a direct comparison with DXA results, with separate analysis for the proximal femur and lumbar spine scans. Additional sub-analysis of the impact of sex, age, and BMI was performed.
After the exclusion of patients due to significant skeletal impairments, missing results, and erroneous reports, 66 scans of the femur and 58 scans of the lumbar spine were analyzed. The diagnostic agreement between the results of DXA and REMS was 82.8% in the lumbar spine group and 84.8% in the femur group. Strong correlations between REMS and DXA results were found in both groups, regardless of the sex, age, and BMI.
Radiofrequency echographic multispectrometry showed a significant diagnostic agreement with the corresponding DXA measurements. The study further confirms the usefulness of REMS in the assessment of osteoporosis.
骨质疏松症在波兰仍未得到充分诊断,部分原因是作为金标准诊断技术的近端股骨和腰椎双能X线吸收测定法(DXA)的可及性有限。使用射频超声多光谱测定法(REMS)作为替代诊断工具可能特别有意义,因为该技术是非电离的,设备便于携带,且使用成本相对较低。
本研究旨在评估一种新型定量技术(REMS)与DXA在评估骨密度和诊断骨质疏松症方面的一致性。
所有招募的患者(n = 116)均接受了近端股骨和腰椎的DXA及REMS检查。通过与DXA结果直接比较来评估REMS的诊断一致性,对近端股骨和腰椎扫描分别进行分析。还对性别、年龄和体重指数的影响进行了额外的亚组分析。
在排除因严重骨骼损伤、结果缺失和报告错误的患者后,分析了66次股骨扫描和58次腰椎扫描。腰椎组DXA与REMS结果的诊断一致性为82.8%,股骨组为84.8%。无论性别、年龄和体重指数如何,两组中REMS与DXA结果均存在强相关性。
射频超声多光谱测定法与相应的DXA测量结果显示出显著的诊断一致性。该研究进一步证实了REMS在评估骨质疏松症方面的有用性。