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用于评估肾移植受者骨骼健康状况的射频超声多光谱技术(REMS)

Radiofrequency Echographic Multi Spectrometry (REMS) Technology for Bone Health Status Evaluation in Kidney Transplant Recipients.

作者信息

Fassio Angelo, Adami Giovanni, Andreola Stefano, Ferraro Pietro Manuel, Pisani Paola, Lombardi Fiorella Anna, Viapiana Ombretta, Rossini Maurizio, Caletti Chiara, Gambaro Giovanni, Gatti Matteo, Gatti Davide

机构信息

Rheumatology Unit, University of Verona, 37134 Verona, Italy.

Nephrology Unit, University of Verona, 37134 Verona, Italy.

出版信息

Diagnostics (Basel). 2024 Sep 23;14(18):2106. doi: 10.3390/diagnostics14182106.

Abstract

: A significant loss in bone density and strength occurs during the post-renal-transplant period with higher susceptibility to fracture. The study aims to compare the performance of the Radiofrequency Echographic Multi Spectrometry (REMS) in the bone mineral density assessment with the conventional dual-energy X-ray absorptiometry (DXA) in a cohort of kidney transplant recipients (KTR). : A cohort of 40 patients underwent both DXA and REMS examinations on the lumbar spine and/or proximal femur. The paired -test was used to compare DXA and REMS measurements; the chi-square test was used to compare the prevalence of osteoporosis/osteopenia. The agreement between the two techniques was assessed through Spearman's correlation. : As expected, most KTR patients were osteopenic or osteoporotic with both REMS and DXA (86.5% and 81% for the femur; 88% and 65% for the lumbar spine < 0.05). A modest correlation (r = 0.4, < 0.01) was observed at the lumbar spine between the T-score measured by REMS and DXA. A strong correlation was defined between REMS and DXA in the femoral region (r = 0.7, < 0.0001). : The study demonstrates the exchangeability of the two techniques on the proximal femur in KTR and a higher diagnostic accuracy of REMS at the spine level than DXA.

摘要

肾移植后骨密度和强度会显著下降,骨折易感性增加。本研究旨在比较射频超声多光谱测定法(REMS)与传统双能X线吸收法(DXA)在一组肾移植受者(KTR)中评估骨矿物质密度的性能。40名患者对腰椎和/或股骨近端进行了DXA和REMS检查。配对t检验用于比较DXA和REMS测量值;卡方检验用于比较骨质疏松症/骨质减少症的患病率。通过Spearman相关性评估两种技术之间的一致性。正如预期的那样,大多数KTR患者使用REMS和DXA检测均显示为骨质减少或骨质疏松(股骨分别为86.5%和81%;腰椎分别为88%和65%,P<0.05)。在腰椎,REMS和DXA测量的T值之间观察到中等相关性(r = 0.4,P<0.01)。在股骨区域,REMS和DXA之间存在强相关性(r = 0.7,P<0.0001)。该研究证明了这两种技术在KTR股骨近端的可互换性,且REMS在脊柱水平的诊断准确性高于DXA。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/356a/11431431/f971f3eb8e5d/diagnostics-14-02106-g001.jpg

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