Lægerne i Hirtshals APS, Hirtshals, Denmark.
Research Unit for Environment, Work and Health, Danish Ramazzini Center, Department of Public Health, Aarhus University, Aarhus, Denmark.
PLoS One. 2021 Jun 28;16(6):e0253319. doi: 10.1371/journal.pone.0253319. eCollection 2021.
Evaluate the accuracy and precision of the copd-6 mini-spirometer for FEV1 in a rural Ugandan population.
In a cross-sectional study, 171 smallholder farmers performed spirometry with copd-6, and a diagnostic-quality spirometer.
The copd-6 underestimated FEV1 at low flows and overestimated FEV1 at high flows. Across all participants, the device slightly overestimated FEV1 by 0.04 [0.02; 0.06] L. Calibration data showed similar patterns.
The copd-6 could be considered as an affordable tool for research on lung function impairment in resource-constrained settings. However, further validation in a study population with obstructive lung disease is needed.
评估 copd-6 小型肺活量计在乌干达农村人群中测量 FEV1 的准确性和精密度。
在一项横断面研究中,171 名小农使用 copd-6 和诊断质量的肺活量计进行了肺活量测定。
copd-6 在低流量时低估了 FEV1,在高流量时高估了 FEV1。在所有参与者中,该设备略微高估了 0.04 [0.02; 0.06] L 的 FEV1。校准数据显示出类似的模式。
copd-6 可以被认为是资源有限环境下研究肺功能障碍的一种经济实惠的工具。然而,还需要在患有阻塞性肺疾病的研究人群中进行进一步验证。