Food Additives Standard Division, Food Standard Planning Office, Ministry of Food and Drug Safety, Osong, Cheongju, 28159, Republic of Korea.
Food Additives Standard Division, Food Standard Planning Office, Ministry of Food and Drug Safety, Osong, Cheongju, 28159, Republic of Korea.
Food Chem Toxicol. 2021 Aug;154:112373. doi: 10.1016/j.fct.2021.112373. Epub 2021 Jun 25.
The safety of food contact plastic materials, including PP, PE, PET, PCT, PLA, PBT and cross-linked polyester, was assessed with regard to migrated substances. The migrated concentrations of overall migrants (OMs), terephthalic acid, acetaldehyde, 1,4-butanediol and lead, were determined according to the standards and specifications for utensils, containers and packages in Korea. Food simulants of 4% acetic acid, water and n-heptane were used for the analysis of the substances. The dietary exposures of terephthalic acid, acetaldehyde and 1,4-butanediol were assessed using the dietary concentrations and the food consumption data. As a result, the dietary exposures were considered to be safe comparing to the health-based guidance values. In the case of lead, the margin of exposure (MOE) approach was applied. The MOEs calculated using the UB concentration and mean consumption data were ranged from 3 to 1000, which indicated low concern for health risk. Moreover, in this study, the dietary exposures were estimated by the Korean MFDS and U.S. FDA methods, respectively. As a result, the assessed risks were considered to be low in both cases. Based on the results of current exposure assessments, it could be considered that the food contact plastic materials are properly controlled by the regulatory authorities.
对食品接触用塑料材料（包括 PP、PE、PET、PCT、PLA、PBT 和交联聚酯）的迁移物进行了安全性评估。根据韩国餐具、容器和包装标准和规范，测定了总迁移量（OM）、对苯二甲酸、乙醛、1,4-丁二醇和铅的迁移浓度。采用 4%乙酸、水和正庚烷作为食品模拟物进行物质分析。通过膳食浓度和食物消费数据评估了对苯二甲酸、乙醛和 1,4-丁二醇的膳食暴露量。结果表明，与基于健康的指导值相比，这些膳食暴露量被认为是安全的。对于铅，采用了暴露量与安全限值比值（MOE）的方法。使用 UB 浓度和平均消费数据计算出的 MOE 范围为 3 至 1000，表明对健康风险的关注程度较低。此外，在这项研究中，膳食暴露量分别由韩国 MFDS 和美国 FDA 方法进行了评估。结果表明，在这两种情况下，评估的风险都较低。基于目前的暴露评估结果，可以认为监管机构对食品接触用塑料材料进行了适当的控制。
