局部晚期乳腺癌新辅助化疗后部分缓解患者腋窝反向绘图的可行性和肿瘤安全性。
Feasibility and Oncological Safety of Axillary Reverse Mapping in Patients With Locally Advanced Breast Cancer and Partial Response After Neoadjuvant Chemotherapy.
机构信息
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy.
Breast Unit, Department of Surgical Science, Policlinico Tor Vergata University, Rome, Italy;
出版信息
In Vivo. 2021 Jul-Aug;35(4):2489-2494. doi: 10.21873/invivo.12529.
BACKGROUND/AIM: Axillary reverse mapping (ARM) aims to identify and preserve arm drainage in order to prevent lymphedema following axillary lymph node dissection. Oncological-safety and feasibility are still debated, especially in patients with locally-advanced breast cancer (LABC). We report the first case of the AXMAP 1.0 study performed in our Institution.
PATIENTS AND METHODS
A 52-year-old patient with a triple-negative LABC and partial response to neoadjuvant chemotherapy underwent axillary lymph-node dissection using fluorescence ARM.
RESULTS
Two lymph-nodes draining the ipsilateral upper arm were identified and were not preserved due to suspicion of malignancy. Pathological examination confirmed the presence of malignancy in both lymph nodes.
CONCLUSION
Further studies should be designed in order to validate the oncological safety of this technique, especially in patients with LABC requiring neoadjuvant chemotherapy.
背景/目的：腋窝反向映射（ARM）旨在识别和保留手臂引流，以预防腋窝淋巴结清扫后发生淋巴水肿。其在肿瘤学方面的安全性和可行性仍存在争议，尤其是在局部晚期乳腺癌（LABC）患者中。我们报告了首例在我院进行的 AXMAP 1.0 研究。
患者和方法
一位 52 岁的三阴性 LABC 患者，新辅助化疗后部分缓解，采用荧光 ARM 行腋窝淋巴结清扫。
结果
识别出两条引流同侧上臂的淋巴结，但由于怀疑恶性，未对其进行保留。病理检查证实两个淋巴结均存在恶性肿瘤。
结论
应设计进一步的研究以验证该技术的肿瘤学安全性，尤其是在需要新辅助化疗的 LABC 患者中。
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