碘化物与二硫代碳酸酯的一种新型自由基乙烯基化反应。

A New Radical Vinylation Reaction of Iodides and Dithiocarbonates.

作者信息

Bertrand Frédérique, Quiclet-Sire Béatrice, Zard Samir Z

机构信息

Institut de Chimie des Substances Naturelles, 91198 Gif-Sur-Yvette (France), Fax: (+33) 1-69-07-72-47.

Additional address: Laboratoire de Synthèse Organique associé au CNRS, Ecole Polytechnique, 91128 Palaiseau Cedex (France), Fax: (+33) 1-69-33-30-10.

出版信息

Angew Chem Int Ed Engl. 1999 Jul 12;38(13-14):1943-1946. doi: 10.1002/(SICI)1521-3773(19990712)38:13/14<1943::AID-ANIE1943>3.0.CO;2-R.

DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1943::AID-ANIE1943>3.0.CO;2-R

PMID:34182663

Abstract

Heavy metals can be avoided with a new radical equivalent of the Heck reaction for aliphatic derivatives in which iodide and dithiocarbonate substituents are replaced by substituted vinyl groups [Eq. (1)]. The reaction enables the introduction of vinyl fragments into a variety of functionalized substrates.

摘要

对于脂肪族衍生物，采用一种新型的Heck反应自由基等价物可避免重金属问题，该反应中碘化物和二硫代碳酸酯取代基被取代的乙烯基取代[方程式(1)]。该反应能够将乙烯基片段引入到各种功能化底物中。