Vesterhus Mette, Wiencke Kristine, Haukeland John Willy, Frigstad Svein Oskar, Karlsen Lars Normann, Jørgensen Kristin Kaasen, Folseraas Trine
Tidsskr Nor Laegeforen. 2021 Jun 22;141(10). doi: 10.4045/tidsskr.20.1045. Print 2021 Jun 29.
Autoimmune hepatitis is a chronic liver disease which, if untreated, can lead to cirrhosis of the liver and liver failure. The majority of patients respond well to standard immunosuppressive therapy, but some experience adverse effects, or lack of treatment efficacy. Diagnosis, assessment of therapeutic response and choice of second-line therapy may be challenging. This article provides a summary of updated knowledge concerning diagnosis and treatment of patients with complex autoimmune hepatitis.
自身免疫性肝炎是一种慢性肝病，若不治疗可导致肝硬化和肝衰竭。大多数患者对标准免疫抑制治疗反应良好，但有些患者会出现不良反应或治疗效果不佳。诊断、评估治疗反应以及选择二线治疗可能具有挑战性。本文总结了关于复杂自身免疫性肝炎患者诊断和治疗的最新知识。
