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Prognostic value of Oncogenetic mutations in pediatric T Acute Lymphoblastic Leukemia: a comparison of UKALL2003 and FRALLE2000T protocols.

作者信息

Taj Mary M, Moorman Anthony V, Hamadeh Lina, Petit Arnaud, Asnafi Vahid, Alby-Laurent Fanny, Vora Ajay, Mansour Marc R, Gale Rosemary, Chevret Sylvie, Moppett John, Baruchel André, Macintyre Elizabeth

机构信息

Royal Marsden Hospital, NHS Foundation Trust, London, UK.

Leukaemia Research Cytogenetics Group, Clinical and Translational Research Institute, Newcastle University, Newcastle upon Tyne, UK.

出版信息

Leukemia. 2022 Jan;36(1):263-266. doi: 10.1038/s41375-021-01334-x. Epub 2021 Jun 28.

DOI:10.1038/s41375-021-01334-x
PMID:34183766
Abstract
摘要

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本文引用的文献

1
A validated novel continuous prognostic index to deliver stratified medicine in pediatric acute lymphoblastic leukemia.一种经验证的新型连续预后指数，可用于儿科急性淋巴细胞白血病的分层医学。
Blood. 2020 Apr 23;135(17):1438-1446. doi: 10.1182/blood.2019003191.
2
Oncogenetic mutations combined with MRD improve outcome prediction in pediatric T-cell acute lymphoblastic leukemia.oncogenetic 突变与微小残留病灶联合可改善儿童 T 细胞急性淋巴细胞白血病的预后预测。
Blood. 2018 Jan 18;131(3):289-300. doi: 10.1182/blood-2017-04-778829. Epub 2017 Oct 19.
3
Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trial.
T 系急性淋巴细胞白血病的分类与风险分层
Blood. 2025 Apr 3;145(14):1464-1474. doi: 10.1182/blood.2023022920.
4
Impact of T-cell Receptor Status on Mutational Landscape and Outcome in T-ALL.T细胞受体状态对T细胞急性淋巴细胞白血病突变图谱及预后的影响
Hemasphere. 2023 Mar 17;7(4):e871. doi: 10.1097/HS9.0000000000000871. eCollection 2023 Apr.
5
Understanding the Notch Signaling Pathway in Acute Myeloid Leukemia Stem Cells: From Hematopoiesis to Neoplasia.了解急性髓系白血病干细胞中的Notch信号通路：从造血到肿瘤形成
Cancers (Basel). 2022 Mar 12;14(6):1459. doi: 10.3390/cancers14061459.
PTEN异常对在英国医学研究委员会UKALL2003试验中接受治疗的儿童T细胞急性淋巴细胞白血病患者预后的影响。
Leukemia. 2016 Jan;30(1):39-47. doi: 10.1038/leu.2015.206. Epub 2015 Jul 29.
4
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and intermediate-risk acute lymphoblastic leukaemia (UKALL 2003): a randomised controlled trial.强化缓解后治疗对临床标准风险和中危急性淋巴细胞白血病儿童和青少年微小残留病定义的高危亚组的影响：一项随机对照试验。(UKALL 2003)
Lancet Oncol. 2014 Jul;15(8):809-18. doi: 10.1016/S1470-2045(14)70243-8. Epub 2014 Jun 9.
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J Clin Oncol. 2013 Dec 1;31(34):4333-42. doi: 10.1200/JCO.2012.48.5292. Epub 2013 Oct 28.
6
Incidence and prognostic relevance of genetic variations in T-cell lymphoblastic lymphoma in childhood and adolescence.儿童和青少年 T 细胞淋巴母细胞淋巴瘤中遗传变异的发生率和预后相关性。
Blood. 2013 Apr 18;121(16):3153-60. doi: 10.1182/blood-2012-12-474148. Epub 2013 Feb 8.
7
Treatment reduction for children and young adults with low-risk acute lymphoblastic leukaemia defined by minimal residual disease (UKALL 2003): a randomised controlled trial.儿童和年轻成人低危急性淋巴细胞白血病微小残留病灶定义下的治疗减少（UKALL 2003）：一项随机对照试验。
Lancet Oncol. 2013 Mar;14(3):199-209. doi: 10.1016/S1470-2045(12)70600-9. Epub 2013 Feb 7.
8
Impact of NOTCH1/FBXW7 mutations on outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on the MRC UKALL 2003 trial.NOTCH1/FBXW7 突变对 MRC UKALL 2003 试验治疗的儿童 T 细胞急性淋巴细胞白血病患者结局的影响。
Leukemia. 2013 Jan;27(1):41-7. doi: 10.1038/leu.2012.176. Epub 2012 Jul 3.
9
Clinical impact of NOTCH1 and/or FBXW7 mutations, FLASH deletion, and TCR status in pediatric T-cell lymphoblastic lymphoma.NOTCH1 和/或 FBXW7 突变、FLASH 缺失和 TCR 状态对儿童 T 细胞淋巴母细胞淋巴瘤的临床影响。
J Clin Oncol. 2012 Jun 1;30(16):1966-73. doi: 10.1200/JCO.2011.39.7661. Epub 2012 Apr 30.
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Effect of mitoxantrone on outcome of children with first relapse of acute lymphoblastic leukaemia (ALL R3): an open-label randomised trial.米托蒽醌对急性淋巴细胞白血病（ALL R3）首次复发儿童结局的影响：一项开放标签随机试验。
Lancet. 2010 Dec 11;376(9757):2009-17. doi: 10.1016/S0140-6736(10)62002-8. Epub 2010 Dec 3.