伊斯兰国家和非伊斯兰国家孕妇阴道及直肠中B族链球菌的患病率：一项系统评价与荟萃分析

Prevalence of Group B Streptococcus in Vagina and Rectum of Pregnant Women of Islamic & Non-Islamic Countries: A Systematic Review and Meta-Analysis.

作者信息

Abbasalizadeh Fatemeh, Pourasghary Sajjad, Shirizadeh Maryam, Mousavi Sanaz, Ghojazadeh Morteza, Hoseinifard Hossein, Salehnia Fatemeh, Nikniaz Leila

机构信息

Department of Obstetrics and Gynecology, Al-Zahra Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Student Research Committee, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Iran J Public Health. 2021 May;50(5):888-899. doi: 10.18502/ijph.v50i5.6106.

BACKGROUND

Group B streptococcus or streptococcus Agalactia is a gram positive beta hemolytic bacteria which is the main factor in neonatal infections. This study aimed at determining the prevalence of GBS in world and clarifying the rate of this infection in Islamic and non-Islamic countries.

METHODS

We performed a systematic search by using different databases including Medline, Scopus, Science Direct, Psycho-Info ProQuest and Web of Science published up to Feb 2019. We undertook meta-analysis to obtain the pooled estimate of prevalence of GBS colonization in Islamic and non-Islamic countries.

RESULTS

Among 3324 papers searched, we identified 245 full texts of prevalence of GBS in pregnancy; 131 were included in final analysis. The estimated mean prevalence of maternal GBS colonization was 15.5% (CI:95% (14.2-17)) worldwide; which was 14% (CI:95% (11-16.8)) in Islamic and 16.3% (CI:95% (14.6-18.1)) in non-Islamic countries and was statistically significant. Moreover, with regards to sampling area, prevalence of GBS colonization was 11.1 in vagina and 18.1 in vagina-rectum.

CONCLUSION

Frequent washing of perineum based on religious instructions in Islamic countries can diminish the rate of GBS colonization in pregnant women.

背景

B族链球菌或无乳链球菌是一种革兰氏阳性β溶血性细菌，是新生儿感染的主要因素。本研究旨在确定全球B族链球菌的流行率，并阐明伊斯兰国家和非伊斯兰国家这种感染的发生率。

方法

我们通过使用不同的数据库进行系统检索，包括截至2019年2月发表的Medline、Scopus、Science Direct、Psycho-Info ProQuest和Web of Science。我们进行了荟萃分析，以获得伊斯兰国家和非伊斯兰国家B族链球菌定植流行率的汇总估计值。

结果

在检索的3324篇论文中，我们确定了245篇关于孕期B族链球菌流行率的全文；131篇纳入最终分析。全球范围内，孕产妇B族链球菌定植的估计平均流行率为15.5%（95%CI：(14.2 - 17)）；在伊斯兰国家为14%（95%CI：(11 - 16.8)），在非伊斯兰国家为16.3%（95%CI：(14.6 - 18.1)），差异具有统计学意义。此外，就采样部位而言，阴道B族链球菌定植流行率为11.1%，阴道 - 直肠为18.1%。