Department of Radiology, The Royal National Orthopaedic Hospital, Brockley Hill, HA7 4LP, Stanmore, UK.
Skeletal Radiol. 2021 Dec;50(12):2365-2380. doi: 10.1007/s00256-021-03853-1. Epub 2021 Jun 29.
Soft tissue sarcomas containing a dominant component of haemorrhage are known to be aggressive tumours associated with a poor prognosis. Importantly, the clinical behaviour and imaging characteristics of extensively haemorrhagic soft tissue sarcomas (also termed telangiectatic soft tissue sarcomas) can resemble those of benign haematomas, particularly those that continue to expand over a prolonged period, so-called chronic expanding haematomas (CEH). The following review evaluates the current literature to identify the clinical, imaging and pathological characteristics of telangiectatic soft tissue sarcomas and to determine features that may help distinguish them from CEH. Ultimately, we suggest that lesions with sizeable regions of internal haemorrhage should be regarded with a high degree of suspicion for underlying malignancy and require referral to a tertiary sarcoma centre, where a carefully planned approach to biopsy and follow-up is needed to avoid errors in diagnosis.
富含大量出血成分的软组织肉瘤是一种侵袭性肿瘤,预后较差。重要的是,广泛出血性软组织肉瘤(也称为毛细血管扩张性软组织肉瘤)的临床行为和影像学特征可能类似于良性血肿的特征,特别是那些持续长时间扩张的血肿,即所谓的慢性进行性血肿(CEH)。以下综述评估了当前的文献,以确定毛细血管扩张性软组织肉瘤的临床、影像学和病理学特征,并确定有助于将其与 CEH 区分开来的特征。最终,我们建议对内部出血面积较大的病变应高度怀疑恶性肿瘤,并需要转介至三级肉瘤中心,在那里需要仔细计划活检和随访方法,以避免诊断错误。