系统评价和荟萃分析维生素 E（α-生育酚）补充剂与糖尿病患者血脂参数的关系。
Systematic review and meta-analyses of vitamin E (alpha-tocopherol) supplementation and blood lipid parameters in patients with diabetes mellitus.
机构信息
Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, University Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
出版信息
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102158. doi: 10.1016/j.dsx.2021.05.031. Epub 2021 May 31.
BACKGROUND AND AIMS
The studies have shown that α-tocopherol supplementation could improve lipid profile in diabetes mellitus (DM) patients. Nonetheless, the result remains inconsistent. Therefore, this meta-analysis was performed to evaluate the efficacy of α-tocopherol supplement on lipid parameters in DM patients.
METHODS
We conducted an extensive search via Cochrane Library, PubMed, Scopus, and Web of Science databases to acquire the reported RCTs up to October 2020.
RESULTS
The results showed no effects of α-tocopherol supplementation on lipid profile in DM patients except when used ≥12 weeks.
CONCLUSIONS
α-tocopherol supplementation in DM patients had no significant effect on lipid profiles.
背景和目的
研究表明，α-生育酚补充剂可以改善糖尿病（DM）患者的血脂谱。然而，结果仍不一致。因此，进行了这项荟萃分析，以评估 α-生育酚补充剂对 DM 患者血脂参数的疗效。
方法
我们通过 Cochrane 图书馆、PubMed、Scopus 和 Web of Science 数据库进行了广泛的搜索，以获取截至 2020 年 10 月报告的 RCT。
结果
结果表明，α-生育酚补充剂对 DM 患者的血脂谱没有影响，除非使用时间≥12 周。
结论
α-生育酚补充剂对 DM 患者的血脂谱没有显著影响。
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