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精神分裂症患者精神科治疗的不连续性,与既往精神科治疗的关系及提供者之间的实践差异:一项回顾性纵向队列研究。

Discontinuity of psychiatric care for patients with schizophrenia, relation to previous psychiatric care and practice variation between providers: a retrospective longitudinal cohort study.

机构信息

Department Psychiatry Amsterdam University Medical Centre - location VUmc, Oldenaller 1, 1081 HJ, Amsterdam, The Netherlands.

Department Psychiatry Amsterdam University Medical Centre - location AMC, Amsterdam, The Netherlands.

出版信息

BMC Psychiatry. 2021 Jun 29;21(1):319. doi: 10.1186/s12888-021-03319-7.

DOI:10.1186/s12888-021-03319-7
PMID:34187433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8244203/
Abstract

BACKGROUND

Patients with schizophrenia need continuous integrated healthcare, but many discontinue their treatment, often experiencing adverse outcomes. The first objective of this study is to assess whether patient characteristics or treatment history are associated with discontinuity of psychiatric elective care. The second objective is to assess whether practice variation between providers of psychiatric care contributes to discontinuity of elective care.

METHODS

A large registry-based retrospective cohort of 9194 schizophrenia patients, who were included if they received elective psychiatric care in December 2014-January 2015. Logistic regression models were used to identify predictive factors of discontinuity of care. The dependent variable was the binary variable discontinuity of care in 2016. Potential independent predictive variables were: age, sex, urbanization, and treatment history in 2013-2014. Practice variation between providers was assessed, adjusting for the case mix of patients regarding their demographic and care utilization characteristics.

RESULTS

12.9% of the patients showed discontinuity of elective psychiatric care in the follow-up year 2016. The risk of discontinuity of care in 2016 was higher in younger patients (between age 18 and 26), patients with a history of receiving less elective psychiatric care, more acute psychiatric care, more quarters with elective psychiatric care without antipsychotic medication, or receiving no elective treatment at all. No evidence for practice variation between providers was found.

CONCLUSIONS

Our findings show that the pattern of previous care consumption is an important prognostic factor of future discontinuity of elective care. We propose that previous care consumption can be used to design strategies to improve treatment retention and focus resources on those most at risk of dropping out.

摘要

背景

精神分裂症患者需要持续的综合医疗保健,但许多人中断治疗,经常出现不良后果。本研究的首要目标是评估患者特征或治疗史是否与精神科择期治疗的中断有关。第二个目标是评估精神科治疗提供者之间的实践差异是否导致择期治疗的中断。

方法

这是一项基于大型登记的回顾性队列研究,纳入了 9194 名精神分裂症患者,如果他们在 2014 年 12 月至 2015 年 1 月期间接受了择期精神科治疗。使用逻辑回归模型来确定治疗中断的预测因素。因变量是 2016 年治疗中断的二项变量。潜在的独立预测变量包括:年龄、性别、城市化程度和 2013-2014 年的治疗史。评估了提供者之间的实践差异,并根据患者的人口统计学和护理利用特征对病例组合进行了调整。

结果

在随访的 2016 年,有 12.9%的患者出现择期精神科治疗中断。在 2016 年,治疗中断的风险在较年轻的患者(18-26 岁之间)、接受较少择期精神科治疗、更多急性精神科治疗、更多个季度接受无抗精神病药物的择期精神科治疗或根本没有接受择期治疗的患者中更高。未发现提供者之间的实践差异的证据。

结论

我们的研究结果表明,以前的护理消费模式是未来择期护理中断的一个重要预后因素。我们建议可以使用以前的护理消费来设计策略,以提高治疗保留率,并将资源集中在那些最有可能退出的患者身上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7413/8244203/429b4a2aed7e/12888_2021_3319_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7413/8244203/3f4f105ddd1b/12888_2021_3319_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7413/8244203/429b4a2aed7e/12888_2021_3319_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7413/8244203/3f4f105ddd1b/12888_2021_3319_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7413/8244203/429b4a2aed7e/12888_2021_3319_Fig2_HTML.jpg

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本文引用的文献

1
Schizophrenia.精神分裂症
N Engl J Med. 2019 Oct 31;381(18):1753-1761. doi: 10.1056/NEJMra1808803.
2
Optimizing Treatment Choices to Improve Adherence and Outcomes in Schizophrenia.优化治疗选择以改善精神分裂症的依从性和结局。
J Clin Psychiatry. 2019 Sep 17;80(5):IN18031AH1C. doi: 10.4088/JCP.IN18031AH1C.
3
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PLoS One. 2019 Sep 12;14(9):e0222046. doi: 10.1371/journal.pone.0222046. eCollection 2019.
4
Suicide in Schizophrenia: An Educational Overview.精神分裂症患者的自杀问题:教育概述。
Medicina (Kaunas). 2019 Jul 10;55(7):361. doi: 10.3390/medicina55070361.
5
Continuity of care and clinical outcomes in the community for people with severe mental illness.严重精神疾病患者在社区中的连续护理和临床结局。
Br J Psychiatry. 2019 May;214(5):273-278. doi: 10.1192/bjp.2018.261.
6
Enhancing the Treatment of Patients With Schizophrenia Through Continuous Care.通过持续护理提高精神分裂症患者的治疗效果。
J Clin Psychiatry. 2019 Feb 19;80(1):al18010ah2c. doi: 10.4088/JCP.al18010ah2c.
7
Agreement between primary care and hospital diagnosis of schizophrenia and bipolar disorder: A cross-sectional, observational study using record linkage.初级保健与医院诊断精神分裂症和双相情感障碍的一致性:使用记录链接的横断面观察研究。
PLoS One. 2019 Jan 7;14(1):e0210214. doi: 10.1371/journal.pone.0210214. eCollection 2019.
8
Trends in mortality in schizophrenia and their implications.精神分裂症死亡率的趋势及其影响。
Acta Psychiatr Scand. 2018 Dec;138(6):489-491. doi: 10.1111/acps.12977.
9
Mortality in schizophrenia: 30-year nationwide follow-up study.精神分裂症的死亡率:30 年全国范围随访研究。
Acta Psychiatr Scand. 2018 Dec;138(6):492-499. doi: 10.1111/acps.12913. Epub 2018 Jun 13.
10
Global Epidemiology and Burden of Schizophrenia: Findings From the Global Burden of Disease Study 2016.全球精神分裂症的流行病学和负担:来自 2016 年全球疾病负担研究的结果。
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