Bohannon L L, Barry J M, Norman D J, Bennett W M
Renal Transplant Service, Oregon Health Sciences University, Portland 97201.
J Urol. 1988 Oct;140(4):810-1. doi: 10.1016/s0022-5347(17)41822-2.
Renal function in a living related kidney donor was evaluated 27 years after unilateral nephrectomy. The patient was normotensive and had no significant proteinuria. Creatinine was 0.8 mg. per dl. and creatinine clearance was 88 ml. per minute per 1.73 m.2 or 152 per cent of the single kidney pre-nephrectomy value. Tubular function assessed by the ability to lower urinary pH in response to an acid load was normal. Biopsy of the transplanted kidney 18 years after donation was histologically normal. This case represents one of the longest followup evaluations of a living related donor reported to date and it argues against any adverse effects of organ donation on the function of the remaining kidney.
对一名活体亲属供肾者在单侧肾切除术后27年的肾功能进行了评估。该患者血压正常，无明显蛋白尿。肌酐为0.8毫克/分升，肌酐清除率为88毫升/分钟/1.73平方米，或为肾切除术前单个肾脏值的152%。通过对酸负荷反应降低尿液pH值的能力评估的肾小管功能正常。捐献18年后移植肾的活检组织学正常。该病例是迄今为止报道的对活体亲属供者最长时间的随访评估之一，它表明器官捐献对剩余肾脏功能没有任何不良影响。
