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臂丛神经的磁共振神经成像(MRN):一例Parsonage Turner综合征及臂丛神经成像的基础综述

Magnetic Resonance Neurography (MRN) of the Brachial Plexus: A Case of Parsonage Turner Syndrome and a Basic Review of Imaging of the Brachial Plexus.

作者信息

Kesserwani Hassan, Faulkner Adriana

机构信息

Neurology, Flowers Medical Group, Dothan, USA.

Radiology, Radiology Associates of Dothan, Dothan, USA.

出版信息

Cureus. 2021 May 25;13(5):e15228. doi: 10.7759/cureus.15228.

Abstract

The Parsonage-Turner syndrome (PTS) or immune-mediated brachial plexopathy is a monophasic illness with well-described semiology and reasonable insights into pathogenesis. With the advent of spectacular advancements in magnetic resonance imaging (MRI) technology directed at shortening the T2 echo times and annihilating the "magic angle" and with short tau inversion recovery (STIR) sequences, we now have a new window into the evolution of inflammatory changes involving the nerve roots, brachial plexus and the peripheral nerves in inflammatory diseases of the nerves. Not only can these imaging modalities exclude other structural pathologies but they can also localise disease of the brachial plexus and outline the extent of disease and so allow the clinician to explore the natural history of immune-mediated brachial plexopathies. Indeed, these imaging sequences can antedate electromyographic findings and they can determine the effects of chronic denervation of muscle and fatty replacement. We present one such case of the PTS in order to demonstrate the power of these imaging modalities. In so doing, we outline some of the very basic correlations between the physics of MRI and pathology of the brachial plexus. An unexpected finding in this case report is the dramatic resolution of power loss following immunotherapy in our patient who had positive image findings on T2-weighted sequences and STIR imaging and who otherwise has had a static course. The implications of these findings are explored and adumbrated on.

摘要

帕森吉-特纳综合征(PTS)或免疫介导性臂丛神经病是一种单相疾病,其症状学已得到充分描述,对发病机制也有合理的认识。随着磁共振成像(MRI)技术取得显著进展,能够缩短T2回波时间并消除“魔角”,同时采用短tau反转恢复(STIR)序列,我们现在对神经炎性疾病中神经根、臂丛神经和周围神经的炎性变化演变有了新的观察窗口。这些成像方式不仅可以排除其他结构性病变,还能定位臂丛神经疾病并勾勒出疾病范围,从而使临床医生能够探究免疫介导性臂丛神经病的自然病程。实际上,这些成像序列能够先于肌电图检查结果出现,并且可以确定肌肉慢性失神经支配和脂肪替代的影响。我们展示这样一例PTS病例,以证明这些成像方式的作用。在此过程中,我们概述了MRI物理学与臂丛神经病理学之间的一些基本关联。本病例报告中的一个意外发现是,我们这位在T2加权序列和STIR成像上有阳性影像表现且病情原本静止的患者,在接受免疫治疗后,力量丧失情况得到了显著缓解。我们探讨并阐述了这些发现的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff89/8232922/e8c85892152f/cureus-0013-00000015228-i01.jpg

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