Jankarashvili Natalia, Melkadze Tamar, Tchiabrishvili Mariam, Mariamidze Armaz, Arveladze Giorgi
Department of Radiation Oncology, Academician Fridon Todua Medical Center, Tbilisi, GEO.
Department of Clinical Oncology, Academician Fridon Todua Medical Center, Tbilisi, GEO.
Cureus. 2021 May 26;13(5):e15255. doi: 10.7759/cureus.15255.
Esophageal carcinoma is the seventh most common cancer and the sixth most lethal cancer worldwide. There are two main histological types of esophageal carcinoma: adenocarcinoma (AC) and squamous cell carcinoma (SCC). Both histological types are more common in males than females. Menopause is an independent risk factor for esophageal cancer while usage of hormonal therapy (estrogen plus progesterone) is associated with a lower risk of esophageal SCC in postmenopausal women. Gender differences have an impact on SCC incidence, however, it is unclear if gender has a prognostic value for survival. The present case report describes a young woman who developed SCC of the esophagus. The disease was diagnosed in the locally advanced stage. Definitive chemo-radiotherapy induced complete response. These findings might suggest that in young women esophageal SCC may have a better prognosis.
食管癌是全球第七大常见癌症和第六大致命癌症。食管癌主要有两种组织学类型：腺癌（AC）和鳞状细胞癌（SCC）。两种组织学类型在男性中都比女性更常见。绝经是食管癌的独立危险因素，而激素治疗（雌激素加孕激素）与绝经后女性食管SCC风险较低相关。性别差异对SCC发病率有影响，然而，性别对生存是否具有预后价值尚不清楚。本病例报告描述了一名患食管SCC的年轻女性。该疾病在局部晚期被诊断出来。确定性放化疗诱导了完全缓解。这些发现可能表明，年轻女性的食管SCC可能预后更好。
