Stefanachi Francesca, Benetti Elisa, Longo Germana, Parolin Mattia, Bonardi Claudia Maria, Meneghesso Davide
Department of Women's and Children's Health, Paediatric Nephrology, Dialysis and Transplant Unit, University Hospital of Padova, Padua, Italy.
Department of Women's and Children's Health, Pediatric Intensive Care Unit, University Hospital of Padova, Padua, Italy.
SN Compr Clin Med. 2021;3(9):1935-1937. doi: 10.1007/s42399-021-01004-0. Epub 2021 Jun 24.
Since April 2020, several paediatric cases were reported with a multisystemic inflammatory syndrome related with SARS-CoV2, called MIS-C. In this case report, we describe a 2-year-old male with end-stage renal disease (ESRD) in renal replacement therapy (RRT) with peritoneal dialysis and severe hypertension affected by a severe SARS-CoV2 related illness characterised by multiorgan failure and need for intensive care, with clinical and instrumental features compatible with MIS-C. Most paediatric patients with kidney disease experience mild SARS-CoV2 disease and to our knowledge, this is the first case of a child with chronic kidney disease suffering from MIS-C. We believe that chronic kidney disease together with dialysis status and severe hypertension play a crucial role on developing severe forms of SARS-CoV2 related disease.
自2020年4月以来，有几例儿科病例报告显示与严重急性呼吸综合征冠状病毒2（SARS-CoV2）相关的多系统炎症综合征，称为儿童多系统炎症综合征（MIS-C）。在本病例报告中，我们描述了一名2岁男性，患有终末期肾病（ESRD），正在接受腹膜透析的肾脏替代治疗（RRT），且患有严重高血压，感染了一种严重的SARS-CoV2相关疾病，其特征为多器官功能衰竭且需要重症监护，临床和影像学特征符合MIS-C。大多数患有肾脏疾病的儿科患者感染SARS-CoV2后病情较轻，据我们所知，这是首例患有慢性肾病的儿童罹患MIS-C。我们认为，慢性肾病、透析状态以及严重高血压在发展为严重形式的SARS-CoV2相关疾病中起着关键作用。
