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First Reported Nosocomial Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 in a Pediatric Dialysis Unit.首例儿童透析病房发生的严重急性呼吸综合征冠状病毒 2 医院感染暴发。
Clin Infect Dis. 2021 Jan 27;72(2):265-270. doi: 10.1093/cid/ciaa491.
2
COVID-19 in Children with Nephrotic Syndrome on Anti-CD20 Chronic Immunosuppression.接受抗CD20慢性免疫抑制治疗的肾病综合征患儿的新型冠状病毒肺炎
Clin J Am Soc Nephrol. 2020 Oct 7;15(10):1494-1495. doi: 10.2215/CJN.06400420. Epub 2020 Jul 10.
3
The severity of COVID-19 in children on immunosuppressive medication.使用免疫抑制药物的儿童感染新冠病毒疾病的严重程度。
Lancet Child Adolesc Health. 2020 Jul;4(7):e17-e18. doi: 10.1016/S2352-4642(20)30145-0. Epub 2020 May 13.
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Asymptomatic Seroconversion of Immunoglobulins to SARS-CoV-2 in a Pediatric Dialysis Unit.儿科透析病房中 SARS-CoV-2 免疫球蛋白无症状血清转化。
JAMA. 2020 Jun 16;323(23):2424-2425. doi: 10.1001/jama.2020.8438.
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How we mitigated and contained the COVID-19 outbreak in a hemodialysis center: Lessons and experience.我们如何在血液透析中心减轻和控制新冠疫情:经验教训
Infect Control Hosp Epidemiol. 2020 Oct;41(10):1240-1242. doi: 10.1017/ice.2020.161. Epub 2020 Apr 23.
6
Coronavirus Infections in Children Including COVID-19: An Overview of the Epidemiology, Clinical Features, Diagnosis, Treatment and Prevention Options in Children.儿童冠状病毒感染包括 COVID-19:儿童流行病学、临床特征、诊断、治疗和预防选择概述。
Pediatr Infect Dis J. 2020 May;39(5):355-368. doi: 10.1097/INF.0000000000002660.
7
Coronavirus Disease 2019 in Children - United States, February 12-April 2, 2020.2019 年冠状病毒病在儿童中的情况-美国,2020 年 2 月 12 日至 4 月 2 日。
MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426. doi: 10.15585/mmwr.mm6914e4.
8
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Clin Infect Dis. 2020 Jul 28;71(15):799-806. doi: 10.1093/cid/ciaa351.
9
Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington.华盛顿州金县长期护理机构中 COVID-19 的流行病学。
N Engl J Med. 2020 May 21;382(21):2005-2011. doi: 10.1056/NEJMoa2005412. Epub 2020 Mar 27.
10
Mitigating Risk of COVID-19 in Dialysis Facilities.降低透析机构中新冠病毒病的风险
Clin J Am Soc Nephrol. 2020 May 7;15(5):707-709. doi: 10.2215/CJN.03340320. Epub 2020 Mar 20.

2019 年冠状病毒病(COVID-19)在两名慢性免疫抑制肾疾病患儿中的病例系列研究

Coronavirus disease 2019 (COVID-19) in two pediatric patients with kidney disease on chronic immunosuppression: A case series.

机构信息

Division of Nephrology, Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.

Division of Infectious Diseases, Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.

出版信息

Hemodial Int. 2021 Jan;25(1):E1-E5. doi: 10.1111/hdi.12876. Epub 2020 Oct 5.

DOI:10.1111/hdi.12876
PMID:33015942
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7675317/
Abstract

Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). While children appear to experience less severe disease than adults, those with underlying conditions such as kidney disease may be more susceptible to infection. Limited data are present for children with kidney disease, and there are limited prior reports of pediatric hemodialysis patients with COVID-19. This report describes the mild clinical disease course of COVID-19 in two pediatric patients with chronic kidney disease, one on hemodialysis and both on chronic immunosuppression. We review treatment in these patients, as well as our measures to reduce transmission among our hemodialysis patients and staff.

摘要

2019 年冠状病毒病(COVID-19)是由严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)引起的高度传染性疾病。尽管儿童的疾病似乎比成年人轻,但那些患有肾脏疾病等潜在疾病的儿童可能更容易感染。目前针对患有肾脏疾病的儿童的数据有限,先前也很少有关于患有 COVID-19 的儿科血液透析患者的报告。本报告描述了两名慢性肾脏疾病儿童患者的 COVID-19 轻度临床疾病过程,其中一名正在接受血液透析,两名均在接受慢性免疫抑制治疗。我们回顾了这些患者的治疗方法,以及我们为减少血液透析患者和工作人员之间传播而采取的措施。