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2019 年冠状病毒病(COVID-19)在两名慢性免疫抑制肾疾病患儿中的病例系列研究

Coronavirus disease 2019 (COVID-19) in two pediatric patients with kidney disease on chronic immunosuppression: A case series.

机构信息

Division of Nephrology, Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.

Division of Infectious Diseases, Department of Pediatrics, Indiana University, Indianapolis, Indiana, USA.

出版信息

Hemodial Int. 2021 Jan;25(1):E1-E5. doi: 10.1111/hdi.12876. Epub 2020 Oct 5.

Abstract

Coronavirus disease 2019 (COVID-19) is a highly infectious disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). While children appear to experience less severe disease than adults, those with underlying conditions such as kidney disease may be more susceptible to infection. Limited data are present for children with kidney disease, and there are limited prior reports of pediatric hemodialysis patients with COVID-19. This report describes the mild clinical disease course of COVID-19 in two pediatric patients with chronic kidney disease, one on hemodialysis and both on chronic immunosuppression. We review treatment in these patients, as well as our measures to reduce transmission among our hemodialysis patients and staff.

摘要

2019 年冠状病毒病(COVID-19)是由严重急性呼吸系统综合征冠状病毒 2 型(SARS-CoV-2)引起的高度传染性疾病。尽管儿童的疾病似乎比成年人轻,但那些患有肾脏疾病等潜在疾病的儿童可能更容易感染。目前针对患有肾脏疾病的儿童的数据有限,先前也很少有关于患有 COVID-19 的儿科血液透析患者的报告。本报告描述了两名慢性肾脏疾病儿童患者的 COVID-19 轻度临床疾病过程,其中一名正在接受血液透析,两名均在接受慢性免疫抑制治疗。我们回顾了这些患者的治疗方法,以及我们为减少血液透析患者和工作人员之间传播而采取的措施。

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