Department of Spine Disorders and Pediatric Orthopaedics, University of Medical Sciences, Poznan, Poland.
Rehasport Clinic, Poznan, Poland.
Stud Health Technol Inform. 2021 Jun 28;280:241-244. doi: 10.3233/SHTI210476.
The Global Lung Function Initiative (GLI 2012) presented multi-ethnic spirometry reference values that are recommended to be used instead previous Zapletals' reference values. The study aimed to compare the values of the pulmonary parameters calculated according to the Zapletals' versus the GLI 2012 reference values in adolescents with idiopathic scoliosis. Preoperative pulmonary testing and radiographic evaluation were performed in 39 adolescents (29 females, 10 males) aged 12-17 years. The thoracic Cobb angle ranged 50°-104°. Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) were measured. The percentages of predicted values of FVC (%FVC) and the FEV1 (%FEV1) were calculated according to the Zapletals' reference values and to the GLI 2012 reference values. The subgroup analysis was performed for the subjects with Cobb curve 50°-74° (N=26) versus the subjects with Cobb curve 75°-104° (N=13). Mean %FVC was significantly higher using the Zapletals' reference values 86.1%±16.4 versus 84.6%±15.6 using the GLI 2012 reference values, p=0.0116. Mean %FEV1 was significantly higher using the Zapletals' reference values 84.5%±18.2 versus 80.0%±16.3 using GLI 2012 reference values, p=0.000001. The subgroup analysis revealed significant difference of %FVC in moderate (p=0.033974) and no difference in severe curves (p=0.1993). The %FEV1 differences were significant in both moderate (p=0.000011) and severe curves (p=0.0334). The study demonstrated that a significant difference might be observed in the spirometry parameters due to the applied reference values. These differences might be taken into account during the spirometry examination interpretation.
全球肺功能倡议（GLI 2012）提出了多民族肺活量参考值，建议用于替代以前的 Zapletals 参考值。本研究旨在比较特发性脊柱侧凸青少年根据 Zapletals 与 GLI 2012 参考值计算的肺参数值。对 39 例青少年（29 名女性，10 名男性）进行术前肺功能检查和影像学评估，年龄 12-17 岁。胸椎 Cobb 角范围 50°-104°。测量用力肺活量（FVC）和 1 秒用力呼气量（FEV1）。根据 Zapletals 参考值和 GLI 2012 参考值计算 FVC 的预计百分比（%FVC）和 FEV1 的预计百分比（%FEV1）。对 Cobb 曲线 50°-74°（N=26）的受试者和 Cobb 曲线 75°-104°（N=13）的受试者进行亚组分析。使用 Zapletals 参考值，%FVC 均值明显更高，为 86.1%±16.4%，而使用 GLI 2012 参考值，%FVC 均值为 84.6%±15.6%，p=0.0116。使用 Zapletals 参考值，%FEV1 均值明显更高，为 84.5%±18.2%，而使用 GLI 2012 参考值，%FEV1 均值为 80.0%±16.3%，p=0.000001。亚组分析显示，中度曲线的%FVC 差异有统计学意义（p=0.033974），重度曲线的%FVC 差异无统计学意义（p=0.1993）。中度和重度曲线的%FEV1 差异均有统计学意义（p=0.000011 和 p=0.0334）。本研究表明，由于应用的参考值，肺功能参数可能会出现显著差异。在肺功能检查解释时应考虑这些差异。
