Department of General Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009.
Affiliated Hospital of Stomatology, School of Stomatology, Zhejiang University School of Medicine, and Key Laboratory of Oral Biomedical Research of Zhejiang Province, Hangzhou 310006, Zhejiang Province, China.
Medicine (Baltimore). 2021 Jul 2;100(26):e26379. doi: 10.1097/MD.0000000000026379.
Pancreatic tail cystic lesions are increasingly encountered in clinical practice, however, it is difficult to make a correct diagnosis preoperatively because there are many types of pancreatic neoplastic and non-neoplastic cysts. Epidermoid cyst in an intrapancreatic accessory spleen (ECIPAS) is a rare non-neoplastic cyst locating in the pancreatic tail, and it is commonly misdiagnosed as another cystic neoplasm.
A 51-year-old man was admitted for investigation of abdominal pain. The physical examination and laboratory tests found no abnormalities, except for an elevation of carbohydrate antigen (CA)19-9. Imaging revealed a cystic lesion within the pancreatic tail, and the solid component surrounding the cyst was enhanced similarly to those of the splenic tissue.
ECIPAS was diagnosed based on the pathology after surgery. The mass was composed of a cyst and brown solid spleen-like tissue. The microscopic analysis demonstrated that the solid component was accessory splenic tissue, and the cyst wall was lined with a thin stratified squamous epithelium.
Laparoscopic spleen-preserving distal pancreatectomy was performed.
The patient was discharged on day 5 postoperatively after an uneventful recovery. CA19-9 returned to normal after surgery. During a 2-years follow-up, there was no evidence of tumor recurrence.
Although rare ECIPAS should be considered in the differential diagnosis of pancreatic tail cystic lesions, and the typical imaging features might facilitate the preoperative diagnosis. Laparoscopic distal pancreatectomy is a safe and effective approach for treating ECIPAS.
胰腺尾部囊性病变在临床实践中越来越常见,但由于胰腺肿瘤性和非肿瘤性囊肿种类繁多,术前很难做出正确诊断。胰腺内副脾表皮样囊肿(ECIPAS)是一种罕见的非肿瘤性囊肿,位于胰腺尾部,常被误诊为另一种囊性肿瘤。
一名 51 岁男性因腹痛入院。体检和实验室检查除了碳水化合物抗原(CA)19-9 升高外无异常。影像学检查显示胰腺尾部有囊性病变,囊性病变周围的实性成分与脾组织增强相似。
术后病理诊断为 ECIPAS。肿块由囊肿和棕色实性脾脏样组织组成。显微镜分析显示,实性成分是副脾组织,囊肿壁内衬有一层薄的复层鳞状上皮。
行腹腔镜保留脾脏的胰体尾切除术。
患者术后第 5 天顺利出院,恢复良好。CA19-9 术后恢复正常。2 年随访期内未见肿瘤复发。
虽然罕见,但 ECIPAS 应在胰腺尾部囊性病变的鉴别诊断中考虑,典型的影像学特征可能有助于术前诊断。腹腔镜胰体尾切除术是治疗 ECIPAS 的一种安全有效的方法。