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海德堡眼科探索者与 ImageJ 软件的光学相干断层扫描厚度测量一致性。

Agreement of optical coherence tomography thickness measurements between Heidelberg Eye Explorer and ImageJ software.

机构信息

Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pa.

Retina Service, Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pa..

出版信息

Can J Ophthalmol. 2022 Oct;57(5):344-349. doi: 10.1016/j.jcjo.2021.05.018. Epub 2021 Jun 27.

DOI:10.1016/j.jcjo.2021.05.018
PMID:34192521
Abstract

OBJECTIVE

To investigate the agreement and correlation of manual central foveal thickness (CFT) measurements using the Heidelberg Eye Explorer and ImageJ software.

METHODS

Optical coherence tomography (OCT) images were identified. CFT was measured using the Heidelberg Eye Explorer caliper tool. Two independent graders measured the CFT of the same images using ImageJ software. A Pearson correlation coefficient, intraclass correlation coefficient, Bland-Altman plots, and coefficient of repeatability were used to assess the agreement and correlation between the Heidelberg Eye Explorer and ImageJ measurements.

RESULTS

One-hundred and twenty-two OCT images from 91 patients were analyzed. Mean CFT as measured using the Heidelberg caliper tool was 264.8 ± 113 µm. Using ImageJ software, graders 1 and 2 obtained mean CFT values of 267 ± 114.3 µm and 270 ± 114.8 µm, respectively. Pearson correlation revealed a strong correlation between the Heidelberg and Image J measurements (r = 0.999, p < 0.0001). Bland-Altman plots noted a less than 4 µm mean difference between Heidelberg and ImageJ CFT values (2.67 ± 3.46 and 3.72 ± 2.78 µm for graders 1 and 2, respectively).

CONCLUSION

There was strong agreement between the Heidelberg Eye Explorer and ImageJ software for manual CFT measurements. ImageJ may be a reliable tool for thickness measurements when proprietary OCT software is unavailable.

摘要

目的

探究海德堡眼科探索者(Heidelberg Eye Explorer)和 ImageJ 软件手动测量中央黄斑厚度(CFT)的一致性和相关性。

方法

识别光学相干断层扫描(OCT)图像。使用海德堡眼科探索者卡尺工具测量 CFT。两名独立的评分者使用 ImageJ 软件测量相同图像的 CFT。采用 Pearson 相关系数、组内相关系数、Bland-Altman 图和可重复性系数来评估海德堡眼科探索者和 ImageJ 测量值之间的一致性和相关性。

结果

对 91 名患者的 122 个 OCT 图像进行了分析。使用海德堡卡尺工具测量的平均 CFT 为 264.8±113 µm。评分者 1 和 2 使用 ImageJ 软件分别获得的平均 CFT 值为 267±114.3 µm 和 270±114.8 µm。Pearson 相关分析显示海德堡和 ImageJ 测量值之间具有很强的相关性(r=0.999,p<0.0001)。Bland-Altman 图显示海德堡和 ImageJ 的 CFT 值之间的平均差异小于 4 µm(评分者 1 和 2 分别为 2.67±3.46 µm 和 3.72±2.78 µm)。

结论

海德堡眼科探索者和 ImageJ 软件在手动 CFT 测量方面具有很强的一致性。当没有专用的 OCT 软件时,ImageJ 可能是一种可靠的厚度测量工具。

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