少突胶质细胞的微环境相互作用。
Microenvironmental interactions of oligodendroglial cells.
机构信息
Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94304, USA.
Department of Neurology and Neurological Sciences, Stanford University, Palo Alto, CA 94304, USA.
出版信息
Dev Cell. 2021 Jul 12;56(13):1821-1832. doi: 10.1016/j.devcel.2021.06.006. Epub 2021 Jun 29.
Abstract
Developmental myelination is a protracted process that extends well into postnatal life. Cell-intrinsic mechanisms operate in myelin-forming oligodendrocytes, as well as microenvironmental interactions that guide and modulate every aspect of myelination, from oligodendrocyte precursor cell migration to oligodendrocyte differentiation and the formation of stable myelin internodes. During development and throughout adult life, neuron-oligodendroglial interactions shape activity and experience-dependent myelin adaptations to fine-tune neural circuit dynamics and promote healthy neurological function.
摘要
发育性髓鞘形成是一个漫长的过程，一直持续到出生后。髓鞘形成少突胶质细胞中的细胞内在机制以及指导和调节髓鞘形成各个方面的微环境相互作用，从少突胶质前体细胞的迁移到少突胶质细胞的分化以及稳定的髓鞘节段的形成。在发育过程中和整个成年期，神经元-少突胶质细胞相互作用塑造了活动和经验依赖性髓鞘适应，以微调神经回路动力学并促进健康的神经功能。
相似文献
1
Microenvironmental interactions of oligodendroglial cells.
Dev Cell. 2021 Jul 12;56(13):1821-1832. doi: 10.1016/j.devcel.2021.06.006. Epub 2021 Jun 29.
2
Impaired Postnatal Myelination in a Conditional Knockout Mouse for the Ferritin Heavy Chain in Oligodendroglial Cells.
J Neurosci. 2020 Sep 30;40(40):7609-7624. doi: 10.1523/JNEUROSCI.1281-20.2020. Epub 2020 Aug 31.
3
Glial and Neuronal Protein Tyrosine Phosphatase Alpha (PTPα) Regulate Oligodendrocyte Differentiation and Myelination.
J Mol Neurosci. 2017 Aug;62(3-4):329-343. doi: 10.1007/s12031-017-0941-x. Epub 2017 Jun 24.
4
The tetraspanin KAI1/CD82 is expressed by late-lineage oligodendrocyte precursors and may function to restrict precursor migration and promote oligodendrocyte differentiation and myelination.
J Neurosci. 2009 Sep 9;29(36):11172-81. doi: 10.1523/JNEUROSCI.3075-09.2009.
5
A Neuron-Free Microfiber Assay to Assess Myelin Sheath Formation.
Methods Mol Biol. 2019;1936:97-110. doi: 10.1007/978-1-4939-9072-6_6.
6
Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish.
Exp Neurol. 2014 Jan;251:72-83. doi: 10.1016/j.expneurol.2013.11.012. Epub 2013 Nov 18.
7
Cytoskeletal Linker Protein Dystonin Is Not Critical to Terminal Oligodendrocyte Differentiation or CNS Myelination.
PLoS One. 2016 Feb 17;11(2):e0149201. doi: 10.1371/journal.pone.0149201. eCollection 2016.
8
Sox2 Is Essential for Oligodendroglial Proliferation and Differentiation during Postnatal Brain Myelination and CNS Remyelination.
J Neurosci. 2018 Feb 14;38(7):1802-1820. doi: 10.1523/JNEUROSCI.1291-17.2018. Epub 2018 Jan 15.
9
Neuron-oligodendroglial interactions in health and malignant disease.
Nat Rev Neurosci. 2023 Dec;24(12):733-746. doi: 10.1038/s41583-023-00744-3. Epub 2023 Oct 19.
10
Building a (w)rapport between neurons and oligodendroglia: Reciprocal interactions underlying adaptive myelination.
Neuron. 2021 Apr 21;109(8):1258-1273. doi: 10.1016/j.neuron.2021.02.003. Epub 2021 Feb 22.
引用本文的文献
1
A functional perspective on astrocyte heterogeneity.
Trends Neurosci. 2025 Jul 21. doi: 10.1016/j.tins.2025.06.009.
2
Neurorehabilitation and white matter repair in traumatic spinal cord injury: a dialogue between clinical and preclinical studies.
Front Neurol. 2025 Jun 18;16:1532056. doi: 10.3389/fneur.2025.1532056. eCollection 2025.
3
Demyelination and Remyelination: General Principles.
Adv Neurobiol. 2025;43:207-255. doi: 10.1007/978-3-031-87919-7_9.
4
Seeing Is Believing: Insights into Myelination and Remyelination in Zebrafish.
Adv Neurobiol. 2025;43:81-95. doi: 10.1007/978-3-031-87919-7_4.
5
Is age-related myelinodegenerative change an initial risk factor of neurodegenerative diseases?
Neural Regen Res. 2026 Feb 1;21(2):648-658. doi: 10.4103/NRR.NRR-D-24-00848. Epub 2025 Jan 13.
6
Low-Intensity Pulsed Ultrasound Promotes Oligodendrocyte Maturation and Remyelination by Down-regulating the Interleukin-17A/Notch1 Signaling Pathway in Mice with Ischemic Stroke.
Research (Wash D C). 2025 Apr 25;8:0676. doi: 10.34133/research.0676. eCollection 2025.
7
The Role of Glial Cells in the Pathophysiology of Epilepsy.
Cells. 2025 Jan 10;14(2):94. doi: 10.3390/cells14020094.
8
Opioid drugs drive electrical insulation of reward circuitry.
Nature. 2024 Jun 5. doi: 10.1038/d41586-024-01630-3.
9
Making Ramón y Cajal proud: Development of cell identity and diversity in the cerebral cortex.
Neuron. 2024 Jul 3;112(13):2091-2111. doi: 10.1016/j.neuron.2024.04.021. Epub 2024 May 15.
10
The neurobiology of SARS-CoV-2 infection.
Nat Rev Neurosci. 2024 Jan;25(1):30-42. doi: 10.1038/s41583-023-00769-8. Epub 2023 Dec 4.
本文引用的文献
1
Neuron class-specific responses govern adaptive myelin remodeling in the neocortex.
Science. 2020 Dec 18;370(6523). doi: 10.1126/science.abd2109.
2
A role of oligodendrocytes in information processing.
Nat Commun. 2020 Oct 30;11(1):5497. doi: 10.1038/s41467-020-19152-7.
3
Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury.
Neuron. 2020 Dec 23;108(6):1130-1145.e5. doi: 10.1016/j.neuron.2020.09.033. Epub 2020 Oct 20.
4
Microglia phagocytose myelin sheaths to modify developmental myelination.
Nat Neurosci. 2020 Sep;23(9):1055-1066. doi: 10.1038/s41593-020-0654-2. Epub 2020 Jul 6.
5
Activity-dependent myelination: A glial mechanism of oscillatory self-organization in large-scale brain networks.
Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13227-13237. doi: 10.1073/pnas.1916646117. Epub 2020 Jun 1.
6
Motor learning promotes remyelination via new and surviving oligodendrocytes.
Nat Neurosci. 2020 Jul;23(7):819-831. doi: 10.1038/s41593-020-0637-3. Epub 2020 May 18.
7
Experience-Dependent Changes in Myelin Basic Protein Expression in Adult Visual and Somatosensory Cortex.
Front Cell Neurosci. 2020 Mar 17;14:56. doi: 10.3389/fncel.2020.00056. eCollection 2020.
8
On the merits of non-invasive myelin imaging in epilepsy, a literature review.
J Neurosci Methods. 2020 May 15;338:108687. doi: 10.1016/j.jneumeth.2020.108687. Epub 2020 Mar 12.
9
Identification of region-specific astrocyte subtypes at single cell resolution.
Nat Commun. 2020 Mar 5;11(1):1220. doi: 10.1038/s41467-019-14198-8.
10
Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation.
Nat Neurosci. 2020 Mar;23(3):363-374. doi: 10.1038/s41593-019-0581-2. Epub 2020 Feb 17.
Zotero 插件