Cicirelli Vincenzo, Aiudi Giulio G, Carbonara Stefano, Caira Michele, Lacalandra Giovani M
Department of Veterinary Medicine, University of Bari "Aldo Moro", Bari, Italy.
IAMB Mediterranean Agronomic Institute of Bari, Bari, Italy.
Top Companion Anim Med. 2021 Nov;45:100554. doi: 10.1016/j.tcam.2021.100554. Epub 2021 Jun 27.
Anorchia is a rare and often poorly understood disorder of sexual development. In the present case report, we used a multidisciplinary approach to diagnose a case of anorchia in a 30-month old dog. The diagnostic process began with gathering the dog medical history followed by a clinical visit with the patient, which included a general wellness examination as well as an examination of the genital system. As suggested in the relevant literature, the dog underwent an ultrasound and then computed tomography (CT) of the genital system, which confirmed the diagnosis of testicular agenesis. Genetic testing confirmed the male XY karyotype. Hormone testing also supported the diagnosis: testosterone and anti-Müllerian hormone levels were below their reference ranges, and luteinizing hormone (LH) was above 1 ng/mL. Following the diagnostic procedures suggested in the relevant literature, the present study confirms anorchia in the dog and describes a case of testicular agenesis in the canine species.
无睾症是一种罕见且常常难以理解的性发育障碍。在本病例报告中,我们采用多学科方法诊断了一例30月龄犬的无睾症。诊断过程始于收集该犬的病史,随后对病犬进行临床检查,包括全面的健康检查以及生殖系统检查。按照相关文献的建议,该犬接受了生殖系统的超声检查,然后进行了计算机断层扫描(CT),这证实了睾丸发育不全的诊断。基因检测证实为男性XY核型。激素检测也支持该诊断:睾酮和抗苗勒管激素水平低于参考范围,而促黄体生成素(LH)高于1 ng/mL。遵循相关文献中建议的诊断程序,本研究证实了该犬患有无睾症,并描述了一例犬类睾丸发育不全的病例。