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使用“Aminogam凝胶”促进犬阴茎损伤手术刮除术后伤口愈合。

Use of 'Aminogam Gel' to fast the wound healing in dogs after the surgical curettage of injured penis.

作者信息

Cicirelli Vincenzo, Accogli Gianluca, Caira Michele, Lacalandra Giovani M, Aiudi Giulio

机构信息

Department of Veterinary Medicine, University of Bari 'Aldo Moro', Bari, Italy.

出版信息

Vet Med Sci. 2022 May;8(3):1001-1007. doi: 10.1002/vms3.769. Epub 2022 Mar 1.

Abstract

BACKGROUND

Aminogam gel is used in human patients to accelerate the post-surgical wound healing process of soft oral tissues (e.g. after teeth extraction or oral laser surgery). For this reason and because of the histological affinity between oral and genital mucosa, Aminogam Gel was applied on the dog's penile mucosa to evaluate wound healing after traumatic lesion.

OBJECTIVES

This study aimed to compare conventional therapy (using only oral medications) to topic application of 'Aminogam Gel' in order to determine which is better to accelerate the healing process of canine penis injuries.

METHODS

For this study, 12 male dogs with an injured penis and traumatic paraphimosis were selected. All patients had traumatic penis injuries due to unsuccessful mating attempts and consequent trauma (continuous licking). The dogs underwent surgical curettage of necrotic areas. The animals were randomly divided into two groups: a control group treated with routine therapy and a group treated with Aminogam Gel as an adjuvant for the scarring process. We assessed wound status and tracked healing using the Bates-Jensen Wound Assessment Tool.

RESULTS

Dogs treated with Aminogam Gel therapy healed faster than dogs treated with traditional therapy alone.

DISCUSSION

Aminogam Gel is a valid auxiliary drug to accelerate wound healing after penis surgery. This is especially important for breeding dogs, for whom rapid and complete healing of the penis is important for returning to normal reproductive activities.

摘要

背景

氨基加凝胶用于人类患者,以加速口腔软组织的术后伤口愈合过程(例如拔牙或口腔激光手术后)。出于这个原因,并且由于口腔和生殖器黏膜之间的组织学相似性,氨基加凝胶被应用于犬的阴茎黏膜,以评估创伤性损伤后的伤口愈合情况。

目的

本研究旨在比较传统疗法(仅使用口服药物)与局部应用“氨基加凝胶”,以确定哪种方法更能加速犬阴茎损伤的愈合过程。

方法

在本研究中,选择了12只阴茎受伤并患有创伤性包皮嵌顿的雄性犬。所有患者均因交配尝试失败及随之而来的创伤(持续舔舐)导致阴茎受伤。这些犬接受了坏死区域的手术刮除。动物被随机分为两组:一组接受常规治疗作为对照组,另一组接受氨基加凝胶治疗作为瘢痕形成过程的辅助治疗。我们使用贝茨-詹森伤口评估工具评估伤口状况并跟踪愈合情况。

结果

接受氨基加凝胶治疗的犬比仅接受传统治疗的犬愈合得更快。

讨论

氨基加凝胶是加速阴茎手术后伤口愈合的有效辅助药物。这对种公犬尤为重要,因为阴茎的快速完全愈合对于恢复正常繁殖活动至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca50/9122447/3025bbe42821/VMS3-8-1001-g009.jpg

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