Emerg Infect Dis. 2021 Sep;27(9):2323-2332. doi: 10.3201/eid2709.204577. Epub 2021 Jun 30.
We characterized common exposures reported by a convenience sample of 202 US patients with coronavirus disease during January-April 2020 and identified factors associated with presumed household transmission. The most commonly reported settings of known exposure were households and healthcare facilities; among case-patients who had known contact with a confirmed case-patient compared with those who did not, healthcare occupations were more common. Among case-patients without known contact, use of public transportation was more common. Within the household, presumed transmission was highest from older (>65 years) index case-patients and from children to parents, independent of index case-patient age. These findings may inform guidance for limiting transmission and emphasize the value of testing to identify community-acquired infections.
我们对 202 名美国 2020 年 1 月至 4 月期间冠状病毒疾病患者的便利样本报告的常见暴露情况进行了描述,并确定了与假定家庭传播相关的因素。报告的已知暴露最常见的环境是家庭和医疗机构;与没有已知接触确诊病例患者的病例患者相比,有已知接触病例患者的病例患者更常见医疗职业。在没有已知接触的病例患者中,更常见使用公共交通工具。在家庭中,假定的传播风险最高的是年龄较大(>65 岁)的索引病例患者,以及儿童向父母的传播,而与索引病例患者的年龄无关。这些发现可能为限制传播提供指导,并强调了检测以识别社区获得性感染的价值。