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屋尘螨脱敏治疗

House dust mite hyposensitization.

作者信息

Newton D A, Maberley D J, Wilson R

出版信息

Br J Dis Chest. 1978 Jan;72(1):21-8. doi: 10.1016/0007-0971(78)90004-9.

DOI:10.1016/0007-0971(78)90004-9
PMID:341952
Abstract

A double-blind controlled trial of house dust mite hyposensitization was carried out in 14 patients with asthma, who were hypersensitive on skin testing to the house dust mite alone. Measurements were made, using a Wright's peak flowmeter, during the 15-month trial period. Precautions were taken in the home to reduce the mite population. At the end of the trial, no clinical improvement was noted subjectively or objectively, despite a reduced bronchial sensitivity to allergen in the treated group. The role of the house dust mite as a cause of asthma is discussed.

摘要

对14名仅对屋尘螨皮肤试验呈超敏反应的哮喘患者进行了屋尘螨脱敏的双盲对照试验。在为期15个月的试验期间,使用赖特峰流速仪进行测量。在家中采取了预防措施以减少螨虫数量。试验结束时,尽管治疗组对过敏原的支气管敏感性降低,但主观或客观上均未观察到临床改善。本文讨论了屋尘螨作为哮喘病因的作用。

相似文献

1
House dust mite hyposensitization.屋尘螨脱敏治疗
Br J Dis Chest. 1978 Jan;72(1):21-8. doi: 10.1016/0007-0971(78)90004-9.
2
Hyposensitization with Dermatophagoides pteronyssinus antigen: trial in asthma induced by house dust.用屋尘螨抗原进行减敏治疗:对屋尘诱发的哮喘的试验
Br Med J. 1971 Oct 23;4(5781):204-6. doi: 10.1136/bmj.4.5781.204.
3
Continuous avoidance measures with or without acaricide in dust mite-allergic asthmatic children.对尘螨过敏的哮喘儿童采用或不采用杀螨剂的持续回避措施。
Ann Allergy Asthma Immunol. 1997 May;78(5):506-12. doi: 10.1016/S1081-1206(10)63239-5.
4
[Therapy of mite asthma (author's transl)].[螨性哮喘的治疗(作者译)]
Z Erkr Atmungsorgane. 1980;155(1):120-4.
5
Three years of specific immunotherapy with house-dust-mite extracts in patients with rhinitis and asthma: significant improvement of allergen-specific parameters and of nonspecific bronchial hyperreactivity.
Allergy. 2001 Apr;56(4):301-6. doi: 10.1034/j.1398-9995.2001.00834.x.
6
Exposure chamber for allergen challenge. A placebo-controlled, double-blind trial in house-dust-mite asthma.变应原激发暴露室。一项针对屋尘螨哮喘的安慰剂对照双盲试验。
Allergy. 1997 Aug;52(8):821-8. doi: 10.1111/j.1398-9995.1997.tb02153.x.
7
[Frequency of sensitization to D. pteronyssinus or D. farinae in children with perennial bronchial asthma].[常年性支气管哮喘患儿对屋尘螨或粉尘螨致敏的频率]
Monatsschr Kinderheilkd. 1985 Apr;133(4):214-8.
8
Hyposensitisation with house dust mite vaccine in bronchial asthma.支气管哮喘患者使用屋尘螨疫苗进行减敏治疗。
Br Med J. 1976 Sep 4;2(6035):561-2. doi: 10.1136/bmj.2.6035.561.
9
Clinical and immunologic evaluation of tyrosine-adsorbed Dermatophagoides pteronyssinus extract: a double-blind placebo-controlled trial.酪氨酸吸附的屋尘螨提取物的临床和免疫学评估:一项双盲安慰剂对照试验。
J Allergy Clin Immunol. 1984 Oct;74(4 Pt 1):524-35. doi: 10.1016/0091-6749(84)90389-0.
10
Effect of hyposensitization upon the immediate and late asthmatic reaction and upon histamine reactivity in patients allergic to house dust mite (Dermatophagoides pteronyssinus).低敏疗法对屋尘螨(粉尘螨)过敏患者速发型和迟发型哮喘反应以及组胺反应性的影响。
Eur Respir J. 1992 Mar;5(3):318-22.

引用本文的文献

1
Specific immunotherapy in house dust mite allergy.室内尘螨过敏的特异性免疫疗法。
Clin Rev Allergy Immunol. 1995 Summer;13(2):151-9. doi: 10.1007/BF02758099.
2
Hyposensitisation to house dust mites.对屋尘螨的减敏疗法
Br Med J. 1980 Mar 1;280(6214):589-90.
3
Hyposensitization in asthma: a review.哮喘中的减敏疗法:综述
J R Soc Med. 1981 Jan;74(1):60-5.
4
Effects of anti-mite measures on children with mite-sensitive asthma: a controlled trial.抗螨措施对螨致敏性哮喘儿童的影响:一项对照试验。
Thorax. 1980 Jul;35(7):506-12. doi: 10.1136/thx.35.7.506.
5
Desensitising vaccines: an allergist's view.脱敏疫苗:过敏症专科医生的观点
Br Med J (Clin Res Ed). 1986 Nov 1;293(6555):1169-70. doi: 10.1136/bmj.293.6555.1169-a.
6
Standardized extracts, dust mite, and other arthropods (inhalants).标准化提取物、尘螨及其他节肢动物(吸入性变应原)。
Clin Rev Allergy. 1987 Feb;5(1):49-73. doi: 10.1007/BF02802257.
7
Immunotherapy in allergic respiratory diseases.过敏性呼吸道疾病的免疫疗法。
Lung. 1990;168 Suppl:1013-24. doi: 10.1007/BF02718239.
8
Canadian consensus on the treatment of asthma in children. Toronto, September, 1990.《加拿大儿童哮喘治疗共识》。多伦多,1990年9月。
CMAJ. 1991 Dec 1;145(11):1449-55.