Gaddie J, Skinner C, Palmer K N
Br Med J. 1976 Sep 4;2(6035):561-2. doi: 10.1136/bmj.2.6035.561.
In a double-blind placebo-controlled trial of tyrosine-absorbed Dermatophagoides pteronyssinus vaccine no improvement was seen in 45 patients with asthma sensitive to house dust mite. In particular there was no significant improvement in symptom scores, spirometry, and skin and nasal challenge test results. Some patients in other studies have benefited from doses of vaccine much stronger than those now commercially available, but the incidence of side effects has also been high.
在一项关于酪氨酸吸收的尘螨疫苗的双盲安慰剂对照试验中，45名对屋尘螨敏感的哮喘患者未见病情改善。特别是症状评分、肺功能测定、皮肤及鼻腔激发试验结果均无显著改善。其他研究中的一些患者受益于比目前市售剂量更强的疫苗，但副作用发生率也很高。
