Abdelghany Ahmed A, D'Oria Francesco, Alio Del Barrio Jorge, Alio Jorge L
Ophthalmology Department, Faculty of Medicine, Minia University, Minia 61519, Egypt.
Section of Ophthalmology, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, 70124 Bari, Italy.
J Clin Med. 2021 Jun 27;10(13):2841. doi: 10.3390/jcm10132841.
Anterior segment optical coherence tomography (AS-OCT) is a modality that uses low-coherence interferometry to visualize and assess anterior segment ocular features, offering several advantages of being a sterile and noncontact modality that generates high-resolution cross-sectional images of the tissues. The qualitative and quantitative information provided by AS-OCT may be extremely useful for the clinician in the assessment of a wide spectrum of corneal infections, guiding in the management and follow-up of these patients. In clinical practice, infections are routinely evaluated with slit-lamp biomicroscopy, an examination and imaging modality that is limited by the physical characteristics of light. As a consequence, the depth of pathology and the eventually associated corneal edema cannot be accurately measured with the slit-lamp. Therefore, it represents a limit for the clinician, as in vivo information about corneal diseases and the response to treatment is limited. Resolution of corneal infection is characterized by an early reduction in corneal edema, followed by a later reduction in infiltration: both parameters can be routinely measured with standardized serial images by AS-OCT.
眼前节光学相干断层扫描（AS-OCT）是一种利用低相干干涉测量法来可视化和评估眼前节眼部特征的检查方法，具有无菌、非接触等优点，能够生成高分辨率的组织横断面图像。AS-OCT提供的定性和定量信息对临床医生评估各种角膜感染、指导这些患者的管理和随访可能极为有用。在临床实践中，感染通常通过裂隙灯生物显微镜检查进行评估，这是一种受光的物理特性限制的检查和成像方法。因此，裂隙灯无法准确测量病理深度以及最终相关的角膜水肿。所以，这对临床医生来说是一个限制，因为关于角膜疾病及其对治疗反应的体内信息有限。角膜感染的消退表现为角膜水肿早期减轻，随后浸润减轻：这两个参数都可以通过AS-OCT的标准化系列图像进行常规测量。
