Byrne Laurann, Hynes Michael J, Connolly Cathal D, Murphy Richard A
Alltech Bioscience Centre, Summerhill Road, Dunboyne, A86 X006 Co. Meath, Ireland.
School of Chemistry, National University of Ireland, H91 TK33 Galway, Ireland.
Animals (Basel). 2021 Jun 10;11(6):1730. doi: 10.3390/ani11061730.
The effect of the chelation process on the pH-dependent stability of organic trace minerals (OTMs) used as mineral supplements in animal nutrition was assessed using analytical techniques such as potentiometry, Fourier Transform Infrared Spectroscopy (FTIRS) and amino acid profiling. The aim was to understand the influence and relative importance of the manufacturing conditions on mineral chelation and the subsequent pH stability of OTMs. A selection of OTMs were assessed over a wide pH range to account for the typical environmental changes encountered in the gastrointestinal (GI) tract. In the case of proteinate type products, the potentiometric assessment of free mineral concentration indicated that the hydrolysis procedure used to generate the chelating peptides was the major influencer of the pH stability of the products. Many products are available under the umbrella term "OTMs", including amino acid complexes, amino acid chelates, polysaccharide complexes and proteinates. Significant differences in the pH-dependent stability of a range of commercially available OTMs were observed.
采用电位滴定法、傅里叶变换红外光谱法（FTIRS）和氨基酸谱分析等分析技术，评估了螯合过程对用作动物营养矿物质补充剂的有机微量元素（OTMs）pH依赖性稳定性的影响。目的是了解生产条件对矿物质螯合以及OTMs后续pH稳定性的影响和相对重要性。在较宽的pH范围内对多种OTMs进行了评估，以考虑胃肠道（GI）中典型的环境变化。对于蛋白盐类产品，游离矿物质浓度的电位滴定评估表明，用于生成螯合肽的水解程序是产品pH稳定性的主要影响因素。许多产品都在“OTMs”这一统称下，包括氨基酸络合物、氨基酸螯合物、多糖络合物和蛋白盐。观察到一系列市售OTMs在pH依赖性稳定性方面存在显著差异。
