Department of Obstetrics & Gynaecology, The Aga Khan University, Nairobi 00100, Kenya.
Department of Population Health, The Aga Khan University, Nairobi 00100, Kenya.
Int J Environ Res Public Health. 2021 Jun 25;18(13):6812. doi: 10.3390/ijerph18136812.
Antenatal stress has been associated with adverse birth outcomes such as fetal growth restriction, low birth weight, and preterm birth. Understanding key determinants of stress in a vulnerable pregnant population has the potential of informing development of targeted cost-effective interventions to mitigate against these adverse birth outcomes. We conducted a secondary analysis of data from 150 pregnant women attending antenatal care services at a rural referral hospital in Kenya. The participants completed a sociodemographic and clinical questionnaire, the Cohen's Perceived Stress Scale (PSS) and gave a hair sample for cortisol and cortisone analysis. The association between selected sociodemographic predictors (age, parity, marital status, maternal education, household income, polygyny, and intimate partner violence) and outcomes (hair cortisol, hair cortisone, and PSS score) was examined using univariate, bivariate and multivariate models. We found a negative association between PSS scores and household income (β = -2.40, = 0.016, 95% CI = -4.36, -0.45). There was a positive association of the ratio of hair cortisone to cortisol with Adolescent age group (β = 0.64, = 0.031, 95% CI = 0.06, 1.22), and a negative association with Cohabitation (β = -1.21, = 0.009, 95% CI = -2.11, -0.31). We conclude that household income influenced psychological stress in pregnancy. Adolescence and cohabitation may have an influence on biological stress, but the nature of this effect is unclear.
产前压力与不良生育结局有关,如胎儿生长受限、低出生体重和早产。了解弱势孕妇群体中压力的关键决定因素有可能为制定有针对性的、具有成本效益的干预措施提供信息,以减轻这些不良生育结局。我们对肯尼亚农村转诊医院接受产前保健服务的 150 名孕妇的数据进行了二次分析。参与者完成了一份社会人口学和临床问卷、科恩感知压力量表(PSS),并提供了头发样本进行皮质醇和皮质酮分析。使用单变量、双变量和多变量模型检查了选定的社会人口学预测因素(年龄、产次、婚姻状况、母亲教育、家庭收入、一夫多妻制和亲密伴侣暴力)与结局(头发皮质醇、头发皮质酮和 PSS 评分)之间的关联。我们发现 PSS 评分与家庭收入呈负相关(β=-2.40,p=0.016,95%CI=-4.36,-0.45)。头发皮质酮与皮质醇的比值与青少年年龄组呈正相关(β=0.64,p=0.031,95%CI=0.06,1.22),与同居呈负相关(β=-1.21,p=0.009,95%CI=-2.11,-0.31)。我们得出结论,家庭收入影响怀孕期间的心理压力。青春期和同居可能对生物压力有影响,但这种影响的性质尚不清楚。