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新型冠状病毒2019感染的皮肤表现——来自罗马尼亚西部最大传染病医院的系列病例

Cutaneous Manifestations in SARS-CoV-2 Infection-A Series of Cases from the Largest Infectious Diseases Hospital in Western Romania.

作者信息

Laza Ruxandra, Musta Virgil Filaret, Nicolescu Narcisa Daniela, Marinescu Adelina Raluca, Mocanu Alexandra, Vilceanu Laura, Paczeyka Roxana, Cut Talida Georgiana, Lazureanu Voichita Elena

机构信息

Department XIII, Discipline of Infectious Diseases, University of Medicine and Pharmacy "Victor Babes" Timisoara, E. Murgu Square, Nr. 2, 300041 Timisoara, Romania.

Clinical Hospital of Infectious Diseases and Pneumophtisiology "Doctor Victor Babes" Timisoara, Gheorghe Adam, Nr. 13, 300310 Timisoara, Romania.

出版信息

Healthcare (Basel). 2021 Jun 25;9(7):800. doi: 10.3390/healthcare9070800.

Abstract

(1) Background: SARS-CoV-2 infection, which appeared as an isolated epidemic outbreak in December 2019, proved to be so contagious that, within 3 months, the WHO declared COVID-19 a pandemic. For one year (pre-vaccination period), the virus acted unhindered and was highly contagious, with a predominantly respiratory-oriented aggression. Although this lung damage, responsible for the more than 3,090,025 deaths, has provided sufficient data to facilitate the understanding of pathogenic mechanisms, other observation data, which meet the quality of emerging clinical aspects, such as rashes, remain without well-defined etiopathogenic support or a well-contoured clinical framework. (2) Methods and Results: We followed the occurrence of cutaneous manifestations in patients hospitalized during the second and third outbreak of SARS-CoV-2 in the main clinics of infectious diseases of our county, Timis, and recorded laboratory investigations and clinical evolution for five suggestive cases. (3) Conclusions: The presented cases, added to many other present and future clinical observations, will allow for better knowledge and understanding of SARS-CoV-2 infection, a requirement that has become a global priority for the entire medical and scientific community.

摘要

(1) 背景:2019年12月出现的严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染最初表现为局部疫情爆发,事实证明其传染性极强,以至于在3个月内,世界卫生组织(WHO)就宣布新型冠状病毒肺炎(COVID-19)为大流行病。在长达一年的时间里(疫苗接种前阶段),该病毒不受阻碍地传播且具有高度传染性,主要侵袭呼吸道。尽管导致超过3,090,025人死亡的肺部损伤提供了足够的数据以助于理解致病机制,但其他符合新出现临床症状质量的观察数据,如皮疹,仍缺乏明确的病因学支持或清晰的临床框架。(2) 方法与结果:我们追踪了在我们县(蒂米什县)主要传染病诊所住院的患者在SARS-CoV-2第二波和第三波疫情期间皮肤表现的发生情况,并记录了5例疑似病例的实验室检查和临床病程。(3) 结论:本文所呈现的病例,以及许多其他当前和未来的临床观察结果,将有助于更好地认识和理解SARS-CoV-2感染,这一需求已成为整个医学和科学界的全球优先事项。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eadd/8304390/a1d481472ea4/healthcare-09-00800-g001.jpg

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