Department of Otorhinolaryngology, Head and Neck Surgery, University of Giessen, Klinikstrasse 33, Ebene -1, 35392 Giessen, Germany.
Institute for Pathology, Justus Liebig University, Langhansstrasse 10, 35392 Gießen, Germany.
Int J Mol Sci. 2021 Jun 24;22(13):6771. doi: 10.3390/ijms22136771.
Salivary gland tumors are a rare tumor entity within malignant tumors of all tissues. The most common are malignant mucoepidermoid carcinoma, adenoid cystic carcinoma, and acinic cell carcinoma. Pleomorphic adenoma is the most recurrent form of benign salivary gland tumor. Due to their low incidence rates and complex histological patterns, they are difficult to diagnose accurately. Malignant tumors of the salivary glands are challenging in terms of differentiation because of their variability in histochemistry and translocations. Therefore, the primary goal of the study was to review the current literature to identify the recent developments in histochemical diagnostics and translocations for differentiating salivary gland tumors.
唾液腺肿瘤是所有组织恶性肿瘤中一种罕见的肿瘤实体。最常见的是恶性黏液表皮样癌、腺样囊性癌和腺泡细胞癌。多形性腺瘤是良性唾液腺肿瘤中最常见的复发性肿瘤。由于其发病率低且组织学模式复杂，因此难以准确诊断。由于唾液腺恶性肿瘤在组织化学和易位方面存在多样性，因此在分化方面具有挑战性。因此，该研究的主要目标是回顾当前文献，以确定在组织化学诊断和易位方面用于区分唾液腺肿瘤的最新进展。
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