Delbressine Jeannet M, Machado Felipe V C, Goërtz Yvonne M J, Van Herck Maarten, Meys Roy, Houben-Wilke Sarah, Burtin Chris, Franssen Frits M E, Spies Yvonne, Vijlbrief Herman, van 't Hul Alex J, Janssen Daisy J A, Spruit Martijn A, Vaes Anouk W
Department of Research and Development, Ciro, 6085 NM Horn, The Netherlands.
NUTRIM School of Nutrition and Translational Research in Metabolism, 6229 HX Maastricht, The Netherlands.
Int J Environ Res Public Health. 2021 Jun 3;18(11):6017. doi: 10.3390/ijerph18116017.
A subgroup of patients recovering from COVID-19 experience persistent symptoms, decreased quality of life, increased dependency on others for personal care and impaired performance of activities of daily living. However, the long-term effects of COVID-19 on physical activity (PA) in this subgroup of patients with persistent symptoms remain unclear. Demographics, self-reported average time spent walking per week, as well as participation in activities pre-COVID-19 and after three and six months of follow-up were assessed in members of online long-COVID-19 peer support groups. Two hundred thirty-nine patients with a confirmed COVID-19 diagnosis were included (83% women, median (IQR) age: 50 (39-56) years). Patients reported a significantly decreased weekly walking time after three months of follow-up (three months: 60 (15-120) min. vs. pre-COVID-19: 120 (60-240) min./week; < 0.05). Six months after the onset of symptoms walking time was still significantly lower compared to pre-COVID-19 but significantly increased compared to three months of follow-up (three months: 60 (15-120) min. vs. six months: 90 (30-150) min.; < 0.05). Patients who experience persistent symptoms after COVID-19 may still demonstrate a significantly decreased walking time six months after the onset of symptoms. More research is needed to investigate long-term consequences and possible treatment options to guide patients during the recovery fromCOVID-19.
一部分从新冠病毒疾病（COVID-19）中康复的患者会出现持续症状、生活质量下降、个人护理对他人的依赖增加以及日常生活活动能力受损。然而，COVID-19对这一有持续症状亚组患者身体活动（PA）的长期影响仍不清楚。对在线长期COVID-19同伴支持小组的成员评估了人口统计学特征、自我报告的每周平均步行时间，以及COVID-19之前和随访三个月及六个月后的活动参与情况。纳入了239例确诊为COVID-19的患者（83%为女性，年龄中位数（四分位间距）：50（39 - 56）岁）。患者报告随访三个月后每周步行时间显著减少（三个月：60（15 - 120）分钟 vs. COVID-19之前：120（60 - 240）分钟/周；<0.05）。症状出现六个月后，步行时间仍显著低于COVID-19之前，但与随访三个月相比显著增加（三个月：60（15 - 120）分钟 vs. 六个月：90（30 - 150）分钟；<0.05）。COVID-19后出现持续症状的患者在症状出现六个月后步行时间可能仍显著减少。需要更多研究来调查长期后果和可能的治疗选择，以指导患者从COVID-19中康复。
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