巴西里约热内卢野生蚊子中寨卡病毒的自然感染与垂直传播
Natural Infection and Vertical Transmission of Zika Virus in Sylvatic Mosquitoes and from Rio de Janeiro, Brazil.
作者信息
Alencar Jeronimo, Ferreira de Mello Cecilia, Brisola Marcondes Carlos, Érico Guimarães Anthony, Toma Helena Keiko, Queiroz Bastos Amanda, Olsson Freitas Silva Shayenne, Lisboa Machado Sergio
机构信息
Laboratório Diptera, Instituto Oswaldo Cruz (FIOCRUZ), Manguinhos 21040-360, Brazil.
Programa de Pós-Graduação em Biologia Animal, Instituto de Biologia, Universidade Federal Rural do Rio de Janeiro, Seropédica 23890-000, Brazil.
出版信息
Trop Med Infect Dis. 2021 Jun 11;6(2):99. doi: 10.3390/tropicalmed6020099.
Zika virus (ZIKV) was recently introduced into the Western Hemisphere, where it is suspected to be transmitted mainly by in urban environments. ZIKV represents a public health problem as it has been implicated in congenital microcephaly in South America since 2015. Reports of ZIKV transmission in forested areas of Africa raises the possibility of its dispersal to non-human-modified environments in South America, where it is now endemic. The current study aimed to detect arboviruses in mosquitoes collected from areas with low human interference in Rio de Janeiro, Brazil. Using a sensitive pan-flavivirus RT-PCR, designed to detect the NS5 region, pools of and , were positive for both ZIKV and yellow fever (YFV). Virus RNA was detected in pools of adult males and females reared from field-collected eggs. Findings presented here suggest natural vertical transmission and infection of ZIKV in and in Brazil.
寨卡病毒（ZIKV）最近传入西半球，据怀疑在城市环境中主要通过[此处原文缺失相关内容]传播。寨卡病毒是一个公共卫生问题，因为自2015年以来，它在南美洲被认为与先天性小头畸形有关。在非洲森林地区寨卡病毒传播的报告增加了其传播到南美洲非人类改造环境的可能性，而南美洲目前已成为寨卡病毒的流行地区。当前的研究旨在检测从巴西里约热内卢人类干预较少地区采集的蚊子中的虫媒病毒。使用一种灵敏的泛黄病毒逆转录聚合酶链反应（RT-PCR）来检测NS5区域，[此处原文缺失相关内容]的样本池对寨卡病毒和黄热病病毒（YFV）均呈阳性。在从野外采集的卵孵化出的成年雄蚊和雌蚊样本池中检测到了病毒RNA。此处呈现的研究结果表明，在巴西，寨卡病毒在[此处原文缺失相关内容]中存在自然垂直传播和感染。
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