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食管高分辨率测压临床实践的差异:一项全国性调查

Variations in Clinical Practice of Esophageal High-resolution Manometry: A Nationwide Survey.

作者信息

Gong Eun Jeong, Choi Soo In, Lee Bong Eun, Min Yang Won, Cho Yu Kyung, Jung Kee Wook, Kim Ji Hyun, Park Moo In

机构信息

Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Gangwon-do, Korea.

Division of Gastroenterology, Department of Internal Medicine, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.

出版信息

J Neurogastroenterol Motil. 2021 Jul 30;27(3):347-353. doi: 10.5056/jnm20217.

DOI:10.5056/jnm20217
PMID:34210899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8266491/
Abstract

BACKGROUND/AIMS: Esophageal high-resolution manometry (HRM) enables the comprehensive evaluation of the esophageal motor function. However, protocols are not uniform and clinical practices vary widely among institutions. This study aims to understand the current HRM practice in Korea.

METHODS

The survey was sent via email through the Korean Society of Neurogastroenterology and Motility. The questions covered descriptive information, preparation, techniques, analysis, and reporting of esophageal HRM.

RESULTS

The survey was completed in 32 (74.4%) out of 43 centers, including 24 tertiary and 8 secondary referral centers. Of the 32 centers, 25 (78.1%) performed HRM in a sitting position, while 7 centers (21.9%) reported performing HRM in a supine position. All the centers utilized single wet swallows as a standard, but the volume, frequency, and interval between swallows varied widely. Sixteen centers (50.0%) applied adjunctive tests, including multiple rapid swallows (n = 16) and rapid drink challenges (n = 9). Parameters assessed and documented in the report were similar. In addition to the assessment of the esophagogastric junction and esophageal body, 27 centers (84.8%) and 18 centers (56.3%) included measurements for the upper esophageal sphincter and the pharynx, respectively, in the HRM protocol.

CONCLUSIONS

We found a variation in the available HRM practice among centers, even though they broadly agreed in the data analysis. Efforts are needed to develop a standardized protocol for HRM measurement.

摘要

背景/目的:食管高分辨率测压(HRM)能够全面评估食管运动功能。然而,相关协议并不统一,各机构的临床实践差异很大。本研究旨在了解韩国目前的HRM实践情况。

方法

通过韩国神经胃肠病学和动力学会以电子邮件方式发送调查问卷。问题涵盖食管HRM的描述性信息、准备工作、技术、分析和报告。

结果

43个中心中有32个(74.4%)完成了调查,其中包括24个三级转诊中心和8个二级转诊中心。在这32个中心中,25个(78.1%)采用坐位进行HRM,而7个中心(21.9%)报告采用仰卧位进行HRM。所有中心均以单次湿吞咽作为标准,但吞咽的体积、频率和间隔差异很大。16个中心(50.0%)应用了辅助测试,包括多次快速吞咽(n = 16)和快速饮水试验(n = 9)。报告中评估和记录的参数相似。除了评估食管胃交界处和食管体部外,分别有27个中心(84.8%)和18个中心(56.3%)在HRM方案中纳入了对食管上括约肌和咽部的测量。

结论

我们发现各中心之间现有的HRM实践存在差异,尽管它们在数据分析方面大致达成一致。需要努力制定标准化的HRM测量方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db9/8266491/76ff0695e1f0/jnm-27-3-347-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db9/8266491/bf6778976b73/jnm-27-3-347-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db9/8266491/76ff0695e1f0/jnm-27-3-347-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db9/8266491/bf6778976b73/jnm-27-3-347-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db9/8266491/76ff0695e1f0/jnm-27-3-347-f2.jpg

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Neurogastroenterol Motil. 2021 Jan;33(1):e13954. doi: 10.1111/nmo.13954. Epub 2020 Jul 26.
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Effect of Body Position on High-resolution Esophageal Manometry Variables and Final Manometric Diagnosis.体位对高分辨率食管测压变量及最终测压诊断的影响
J Neurogastroenterol Motil. 2020 Jul 30;26(3):335-343. doi: 10.5056/jnm20010.
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The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.
1990 年至 2017 年全球 195 个国家和地区胃食管反流病的全球、区域和国家负担:2017 年全球疾病负担研究的系统分析。
Lancet Gastroenterol Hepatol. 2020 Jun;5(6):561-581. doi: 10.1016/S2468-1253(19)30408-X. Epub 2020 Mar 13.
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Normative Values for Esophageal Motility Assessed in the Physiological Seated Position for 16-Channel Water Perfused High-resolution Esophageal Manometry System and Postural Variations in Healthy Volunteers.16通道水灌注高分辨率食管测压系统在生理坐姿下评估食管动力的正常参考值及健康志愿者的姿势变化
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British Society of Gastroenterology guidelines for oesophageal manometry and oesophageal reflux monitoring.英国胃肠病学会食管测压和食管反流监测指南。
Gut. 2019 Oct;68(10):1731-1750. doi: 10.1136/gutjnl-2018-318115. Epub 2019 Jul 31.
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Advancements in the use of manometry and impedance testing for esophageal functional disorders.食管功能障碍的测压和阻抗检测应用进展。
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High-resolution impedance manometry parameters in the evaluation of esophageal function of non-obstructive dysphagia patients.高分辨率阻抗测压参数在非梗阻性吞咽困难患者食管功能评估中的应用。
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Which Provocation Test Will Be Added to Routine High-resolution Manometry Protocol in Unexplained Dysphagia?在不明原因的吞咽困难中,哪种激发试验将被添加到常规高分辨率测压方案中?
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