Udomkarnjananun Suwasin, Naiyarakseree Nuanjanthip, Townamchai Natavudh, Surinrat Ekkapong, Tiankanon Kanitha, Banjongjit Athiphat, Vanichanan Jakapat, Jutivorakool Kamonwan, Putcharoen Opass, Suankratay Chusana, Surintrspanont Jerasit, Iampenkhae Kroonpong, Leelahavanichkul Asada, Wattanatorn Salin, Apisutimaitri Kirada, Burimsittichai Rattanaporn, Ratchanon Supoj, Nonthasoot Bunthoon, Sirichindakul Boonchoo, Praditpornsilpa Kearkiat, Avihingsanon Yingyos
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Renal Immunology and Transplantation Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
SAGE Open Med Case Rep. 2021 Jun 18;9:2050313X211024471. doi: 10.1177/2050313X211024471. eCollection 2021.
Patients with human immunodeficiency virus infection are at risk of chronic kidney disease and end-stage renal disease. Human immunodeficiency virus infection impedes patients' accessibility to transplantation in Thailand and other developing countries in Southeast Asia, where the burdens of human immunodeficiency virus infection and chronic kidney disease are rapidly increasing. We report the successful kidney transplantation in a human immunodeficiency virus-positive recipient in Thailand and provide brief information about the current knowledge of human immunodeficiency virus medicine and transplantation that are needed for conducting kidney transplantations in such patients. Patient selection and evaluation, the choice of antiretroviral therapy, immunosuppressive regimens, and infectious complications are reviewed and discussed. The aim is to encourage kidney transplantation in end-stage renal disease patients with well-controlled human immunodeficiency virus infection, especially in countries where the prevalence of human immunodeficiency virus infection is high and the accessibility to transplantation is still limited.
感染人类免疫缺陷病毒的患者有患慢性肾脏病和终末期肾病的风险。在泰国及东南亚其他发展中国家，人类免疫缺陷病毒感染阻碍了患者获得移植的机会，而在这些国家，人类免疫缺陷病毒感染和慢性肾脏病的负担正在迅速增加。我们报告了泰国一名人类免疫缺陷病毒阳性受者成功进行肾移植的病例，并提供了在此类患者中进行肾移植所需的关于人类免疫缺陷病毒医学和移植的当前知识的简要信息。对患者的选择和评估、抗逆转录病毒疗法的选择、免疫抑制方案以及感染并发症进行了回顾和讨论。目的是鼓励在人类免疫缺陷病毒感染得到良好控制的终末期肾病患者中进行肾移植，特别是在人类免疫缺陷病毒感染率高且移植机会仍然有限的国家。
