HIV 感染者的肾移植。
Kidney Transplantation in Patients with HIV.
机构信息
Renal, Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
出版信息
Kidney360. 2020 May 6;1(7):705-711. doi: 10.34067/KID.0002112020. eCollection 2020 Jul 30.
Abstract
Individuals with HIV are at increased risk for ESKD. Kidney transplantation is the best treatment for ESKD in the HIV+ population. Despite reduced access to transplantation, patients who are HIV+ have excellent outcomes and clearly benefit from receiving one. Common post-transplant complications and management concerns, including the optimal antiretroviral regimen, immunosuppression protocols, infectious prophylaxis, hepatitis C coinfection, metabolic complications, and malignancy are all discussed.
摘要
HIV 感染者患 ESKD 的风险增加。对于 HIV 阳性人群，肾移植是 ESKD 的最佳治疗方法。尽管移植机会减少，但 HIV 阳性患者的预后良好，并且从接受移植中明显获益。共同的移植后并发症和管理关注点，包括最佳抗逆转录病毒治疗方案、免疫抑制方案、感染预防、丙型肝炎合并感染、代谢并发症和恶性肿瘤等均在讨论范围内。
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