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一项使用诊断工具——脉搏血氧饱和度测定法来确定接受放疗的口咽癌患者牙髓活力的临床研究。

A Clinical Study Determining Pulp Vitality in Oropharyngeal Cancer Patients Undergoing Radiotherapy Using Diagnostic Tool-Pulse Oximetry.

作者信息

Daveshwar Shilpi R, Kapoor Sonali V, Daveshwar Meena R

机构信息

Department of Dentistry, Gmers Medical College & Hospital, Himmatnagar, Gujarat, India.

Department of Conservative dentistry & Endodontics, Manubhai Patel Dental College and Oral Research Institute, Vadodara, Gujarat, India.

出版信息

Curr Health Sci J. 2021 Jan-Mar;47(1):5-9. doi: 10.12865/CHSJ.47.01.01. Epub 2021 Mar 31.

DOI:10.12865/CHSJ.47.01.01
PMID:34211740
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8200620/
Abstract

Pulse oximetry is an equipment that evaluates pulp vitality for concrete endodontic diagnosis and treatment plan. One of the treatment methods of oropharyngeal cancer is radiotherapy. Radiotherapy has some harmful effects on dental pulp that affects pulp vitality. The objective of study was to assess pulp vitality before, at the end of radiotherapy and six months after radiotherapy (RT) in oropharyngeal cancer patients undergoing radiotherapy. 25 patients who were diagnosed with oropharyngeal cancer having asymptomatic intact crowns were selected for the study. Pulp vitality was checked before the commencement of radiotherapy (PV1), immediately after radiotherapy (PV 2) and six months post radiotherapy (PV 3). Pulp vitality of first posterior tooth was selected of each patient and was checked with pulse oximetry. Paired t-test was used as statistical analysis. Statistically significant difference was observed when PV 1 and PV 2, PV 1 and PV 3 and PV 2 and PV 3 were compared amongst each other. There was reduction noted in mean SpO2 value when groups PV 2 and PV1 were compared. This was statistically significant. Statistically significant increase in mean SpO2 value was observed six months post radiotherapy (PV 3). Thus, it can be concluded that statistically significant reduction in mean SpO2 level post radiotherapy recovers after six months.

摘要

脉搏血氧测定法是一种用于评估牙髓活力以制定具体牙髓病诊断和治疗方案的设备。口咽癌的治疗方法之一是放射治疗。放射治疗对牙髓有一些有害影响,会影响牙髓活力。本研究的目的是评估接受放射治疗的口咽癌患者在放疗前、放疗结束时以及放疗后六个月的牙髓活力。选择25例被诊断为口咽癌且牙冠完整无症状的患者进行研究。在放疗开始前(PV1)、放疗结束后立即(PV2)以及放疗后六个月(PV3)检查牙髓活力。选取每位患者的第一颗后牙,用脉搏血氧测定法检查牙髓活力。采用配对t检验进行统计分析。在比较PV1与PV2、PV1与PV3以及PV2与PV3时,观察到有统计学意义的差异。比较PV2和PV1组时,平均SpO2值有所降低,这具有统计学意义。放疗后六个月(PV3)观察到平均SpO2值有统计学意义的升高。因此,可以得出结论,放疗后平均SpO2水平有统计学意义的降低在六个月后恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaa2/8200620/91e4928fe3a2/CHSJ-47-01-5-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaa2/8200620/fcd7978295e7/CHSJ-47-01-5-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaa2/8200620/91e4928fe3a2/CHSJ-47-01-5-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaa2/8200620/fcd7978295e7/CHSJ-47-01-5-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eaa2/8200620/91e4928fe3a2/CHSJ-47-01-5-fig2.jpg

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本文引用的文献

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Effect of Radiotherapy on Cariogenic Organism Streptococcus sobrinus in Saliva in Head and Neck Cancer: A Clinical Study.
J Contemp Dent Pract. 2018 Aug 1;19(8):929-932.
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Assessment of Pulp Oxygen Saturation Levels by Pulse Oximetry for Pulpal Diseases -A Diagnostic Study.通过脉搏血氧饱和度测定法评估牙髓疾病的牙髓氧饱和度水平——一项诊断性研究
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Late Effects of Head and Neck Radiotherapy on Pulp Vitality Assessed by Pulse Oximetry.通过脉搏血氧测定法评估头颈部放疗对牙髓活力的远期影响。
J Endod. 2016 Jun;42(6):886-9. doi: 10.1016/j.joen.2016.02.016. Epub 2016 Apr 9.
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Clinical diagnosis of pulp inflammation based on pulp oxygenation rates measured by pulse oximetry.基于脉搏血氧仪测量的牙髓氧合率对牙髓炎症进行临床诊断。
J Endod. 2012 Jul;38(7):880-3. doi: 10.1016/j.joen.2012.03.027. Epub 2012 May 18.
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