Kamalapathy Pramod N, Wang Kevin Y, Puvanesarajah Varun, Raad Micheal, Hassanzadeh Hamid
Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.
Department of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Global Spine J. 2023 Jun;13(5):1267-1272. doi: 10.1177/21925682211026913. Epub 2021 Jul 2.
Retrospective cohort study.
The purpose was to compare rates of postoperative ED visits, readmission, and reoperation between patients with and without preexisting mental illness undergoing outpatient anterior cervical discectomy and fusion (ACDF).
A retrospective review of the Mariner Database was conducted on patients who underwent ACDF between 2010 and 2017. Exclusion criteria included same day revision surgery and patients with a history of spine infection, trauma, or neoplasm. Patients were grouped into 3 categories: those with existing history of anxiety and/or depression, those with severe mental illness, and those without any history of mental illness. Severe mental illness was defined as a combination of diagnosis including schizophrenia, bipolar disorder, and/or psychotic disorder. Outcome measures were analyzed by comparing groups using multivariate logistic regression. Significance was set at < 0.05.
Patients with anxiety/depression and patients with severe mental illness both had significantly increased risk of ED visits and readmission at 30-day and 90-day intervals. Compared to patients without mental illness, patients with severe mental illness (OR 1.93, < 0.001) had significantly increased rates of reoperation at 90-days and 1-years postoperatively. Patients with anxiety/depression did not have increased rates of reoperation relative to patients without anxiety/depression at any time interval ( > 0.05).
Anxiety/depression as well as more severe psychiatric disease such as Schizophrenia and Bipolar disorder were significantly associated with increased healthcare utilization following outpatient ACDF. Patients with preexisting mental illness undergoing outpatient ACDF should be carefully evaluated preoperatively and closely followed postoperatively to reduce risk of adverse events.
回顾性队列研究。
比较接受门诊前路颈椎间盘切除融合术(ACDF)的有和无既往精神疾病患者的术后急诊就诊率、再入院率和再次手术率。
对2010年至2017年间接受ACDF手术的患者的水手数据库进行回顾性分析。排除标准包括同日翻修手术以及有脊柱感染、创伤或肿瘤病史的患者。患者分为三类:有焦虑和/或抑郁病史的患者、患有严重精神疾病的患者以及无任何精神疾病史的患者。严重精神疾病定义为包括精神分裂症、双相情感障碍和/或精神病性障碍的诊断组合。通过多因素逻辑回归比较各组分析结局指标。显著性设定为<0.05。
焦虑/抑郁患者和严重精神疾病患者在30天和90天间隔时急诊就诊和再入院的风险均显著增加。与无精神疾病的患者相比,患有严重精神疾病的患者(比值比1.93,<0.001)在术后90天和1年时再次手术率显著增加。在任何时间间隔,焦虑/抑郁患者与无焦虑/抑郁患者相比,再次手术率均未增加(>0.05)。
焦虑/抑郁以及更严重的精神疾病如精神分裂症和双相情感障碍与门诊ACDF术后医疗资源利用增加显著相关。接受门诊ACDF的有既往精神疾病的患者应在术前仔细评估,并在术后密切随访以降低不良事件风险。