2020 年 11 月丹麦科特布斯检出携带 NDM-1 耐药基因的病例。
A case of NDM-1-positive Kottbus, Denmark, November 2020.
机构信息
Department of Clinical Microbiology, Aalborg University Hospital, Aalborg, Denmark.
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
出版信息
Euro Surveill. 2021 Jul;26(26). doi: 10.2807/1560-7917.ES.2021.26.26.2100569.
We present a case of carbapenemase-producing NDM-1-positive Kottbus in an 82-year-old Danish man. The NDM-1 was also identified in and in the same patient on the same 43 kb IncN2 plasmid, suggesting in vivo inter-species plasmid transfer. A NCBI BLAST analysis of the plasmid (pAMA003584_NDM-1) identified 12 highly similar plasmids, all originating from east and south-east Asia. This case could be the first confirmed case of NDM-1-positive not related to travel outside Europe.
我们报告了一例产碳青霉烯酶的 NDM-1 阳性克劳斯鲍在 82 岁丹麦男子。NDM-1 也被鉴定为在同一患者的 和 上相同的 43 kb IncN2 质粒上，提示体内种间质粒转移。对质粒（pAMA003584_NDM-1）的 NCBI BLAST 分析鉴定出 12 个高度相似的质粒，均来自东亚和东南亚。该病例可能是首例与欧洲以外旅行无关的 NDM-1 阳性 确诊病例。
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