Unit of Dermatology, Department of Medical Science and Public Health, University of Cagliari.
Laboratory Clinical Chemical Analysis and Microbiology University Hospital of Cagliari.
Acta Biomed. 2021 Jul 1;92(3):e2021139. doi: 10.23750/abm.v92i3.10100.
Emergent pathogen as Purpureocillium lilacinum are becoming cause of morbidity and mortality in our population, especially in immunocompromised patients. We describe a case of hyalohyphomycosis in a diabetic man under systemic steroid treatment for a bullous pemphigoid. Treatment with different antimycotic drugs were ineffective and infection spread diffusely, leading to deterioration of general conditions and ultimately death. The aim of this article is to increase awareness of clinicians about this uncommon, but frequently fatal refractory mycotic infection.
新兴病原体如枝顶孢霉正在成为我们人群发病和死亡的原因，尤其是在免疫功能低下的患者中。我们描述了一例糖尿病患者在系统性类固醇治疗大疱性类天疱疮时发生的透明丝孢霉病。不同抗真菌药物的治疗均无效，感染广泛扩散，导致一般情况恶化，最终死亡。本文的目的是提高临床医生对这种不常见但经常致命的难治性真菌感染的认识。
