Pu Qing, He Yuyu, Yuan Liming
Department of Chemistry, Yunnan Normal University, Kunming 650500, China.
Se Pu. 2020 Apr 8;38(4):484-489. doi: 10.3724/SP.J.1123.2019.07032.
Chiral mesoporous materials have widely applications in chiral separation, asymmetric catalysis, and chiral sensing. Chiral order inorganic mesoporous silica (COIMS) is a kind of chiral materials with high order mesoporous structure not containing organic component. Here we report that a COIMS diluted with a polysiloxane OV-1701 was explored as a novel stationary phase for capillary gas chromatography. The COIMS was synthesized from D-phenylalanine chiral source, and its separation properties of the chiral column were investigated. Eight enantiomers including chiral alcohols, dialcohols, esters and amino acid derivative have been resolved on the coated capillary column. In addition, COIMS chiral column also exhibits good selectivity for the separations of linear alkanes and alcohols. This work indicates that the column has the advantages of high temperature resistance and short analysis time, so it has great potential to develop it as a chiral stationary phase at high temperature.
手性介孔材料在手性分离、不对称催化和手性传感等方面有着广泛的应用。手性有序无机介孔二氧化硅（COIMS）是一种具有高阶介孔结构且不含有机成分的手性材料。在此我们报道，用聚硅氧烷OV - 1701稀释的COIMS被开发为一种新型的毛细管气相色谱固定相。该COIMS由D - 苯丙氨酸手性源合成，并对手性柱的分离性能进行了研究。在涂覆的毛细管柱上已拆分了包括手性醇、二醇、酯和氨基酸衍生物在内的8种对映体。此外，COIMS手性柱对线性烷烃和醇的分离也表现出良好的选择性。这项工作表明该柱具有耐高温和分析时间短的优点，因此将其开发为高温手性固定相具有很大潜力。
