School of Life Science, Beijing Institute of Technology, Beijing, China.
Chirality. 2020 Sep;32(9):1178-1185. doi: 10.1002/chir.23263. Epub 2020 Jul 5.
Herein, we describe a new chiral amorphous metal-organic polyhedra used as the stationary phase for high-resolution gas chromatography (GC). The chiral stationary phase was coated onto a capillary column via a dynamic coating process and investigated for a variety of compounds. The experimental results showed that the chiral stationary phase exhibits good selectivity for linear alkanes, linear alcohols, polycyclic aromatic hydrocarbons, isomers, and chiral compounds. In addition, the column has the advantages of high column efficiency and short analysis time. The present work indicated that amorphous metal-organic polyhedra have great potential for application as a new type of stationary phase for GC.
本文描述了一种新型的手性无定形金属有机多面体，可用作高分辨气相色谱（GC）的固定相。手性固定相通过动态涂覆过程涂覆在毛细管柱上，并对各种化合物进行了研究。实验结果表明，手性固定相对直链烷烃、直链醇、多环芳烃、异构体和手性化合物具有良好的选择性。此外，该柱具有柱效高、分析时间短的优点。本工作表明，无定形金属有机多面体作为 GC 新型固定相具有很大的应用潜力。
