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眼眶减压术治疗内分泌性眼眶病的疗效及其对生活质量的影响:一项回顾性研究。

Effectiveness of orbital decompression for endocrine orbitopathy and impact on quality of life: A retrospective study.

机构信息

Unit of Cranio Maxillo Facial Surgery, Center for Craniofacial Deformities & Orbital Surgery - Reference Center for Rare Disease, Sant'Anna Hospital and University, Cona, Ferrara, Italy.

Unit of Cranio Maxillo Facial Surgery, Center for Craniofacial Deformities & Orbital Surgery - Reference Center for Rare Disease, Sant'Anna Hospital and University, Cona, Ferrara, Italy.

出版信息

J Craniomaxillofac Surg. 2021 Sep;49(9):867-874. doi: 10.1016/j.jcms.2021.03.001. Epub 2021 Apr 28.

DOI:10.1016/j.jcms.2021.03.001
PMID:34218976
Abstract

To evaluate the effectiveness of orbital decompression intervention in terms of variation of the exophthalmos and to highlight its association with changes in quality of life before and after surgery. Medical records of patients with moderate-severe GO who underwent orbital decompression surgery were retrospectively reviewed. Clinical parameters, including demographic characteristics, surgical technique, exophthalmos values, and QoL using the GO-QoL questionnaire were studied before and after orbital decompression and analyzed. Thirty patients were included in the study. Surgery was bilateral 26 patients and unilateral in 4 patients (56 operated orbits). Before surgery the average value of exophthalmometry was 24.96 (±2.68) mm. The questionnaires submitted for assessment of the quality of life (GO-QoL) yielded average values of 43.3 for the visual function (VF) and 44.03 for the appearance (AP). 20 patients (64.3%) underwent combined bone and fat decompression surgery, 9 underwent fat decompression, and 1 underwent bone decompression. After surgery, the average values of exophthalmometry were 21.8 (±2.34) mm, with an average reduction of 3.20 (±2.35) mm. (p < 0.0001) GO-QoL questionnaires administered after surgery showed a mean VF score of 76.73 (±26.75), and AP score of 73.71 (±21.89). (p < 0.001, paired t-test) Orbital decompressive surgery is not only effective on GO, but also on a long-term improvement in overall well-being, self-confidence and QoL.

摘要

目的

评估眼眶减压干预在外凸变化方面的有效性,并强调其与手术前后生活质量变化的相关性。

方法

回顾性分析接受眼眶减压手术的中重度 GO 患者的病历。研究了临床参数,包括人口统计学特征、手术技术、眼眶减压前后的突眼值以及使用 GO-QoL 问卷评估的生活质量。

结果

共纳入 30 例患者,手术为双侧 26 例,单侧 4 例(56 个手术眼眶)。手术前平均眼突出度为 24.96(±2.68)mm。提交用于评估生活质量(GO-QoL)的问卷得出视觉功能(VF)的平均值为 43.3,外观(AP)的平均为 44.03。20 例(64.3%)患者接受了骨和脂肪联合减压手术,9 例接受了脂肪减压手术,1 例接受了骨减压手术。手术后,平均眼突出度为 21.8(±2.34)mm,平均减少 3.20(±2.35)mm(p<0.0001)。手术后的 GO-QoL 问卷显示,VF 平均评分为 76.73(±26.75),AP 评分为 73.71(±21.89)(p<0.001,配对 t 检验)。

结论

眼眶减压手术不仅对 GO 有效,而且对整体幸福感、自信和生活质量的长期改善也有效。

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